Two patients developed recurrent chorea while receiving oral contraceptives. Chorea associated with oral contraceptives occurs in patients who have had previous episodes of chorea associated with streptococcal infection, rheumatic fever, or pregnancy. Abnormal movements are unilateral and usually develop one to three months after first taking contraceptives. Choreiform movements remit within one to two months after stopping contraceptive medication. Contraceptive therapy should be considered as a possible cause of recurrent chorea. (25:112-114, 1971) Key Words.-Chorea, Sydenham's; oral contraceptive; chorea gravidarum; rheumatic fever. SYDENHAM'S chorea is a disease of childhood; over 80% of cases occur in children between the ages of 5 and 15 years.' In children, the movement disorder is most often a manifestation of rheumatic fever. In adults, however, nonrheumatic causes must also be considered. These include disseminated lupus erythematosus, Sch6nlein-Henoch purpura, polycythemia vera, hypocalcemia, hyperthyroidism, carbon monoxide poisoning, cerebral infarction, intracranial tumors, and bacterial and viral infection.
She was followed up regularly for almost two years and showed no signs of relapse. She stopped taking antithyroid drugs several times and suffered brief relapses of hyperthyroidism, but without any psychosis. CommentHyperthyroidism commonly presents with mental changes such as irritability and anxiety, but psychotic symptoms like hallucination and delusion are rare. The review by Ellis and Mellsop shows that de C1erambault's syndrome is also rare.Our case satisfied all the criteria of the syndrome, but it did not run a chronic course. The prognosis of the primary disorder is generally poor,23 but in this case of secondary erotomania the outcome was good.
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