Quantitative fFN testing adds value to qualitative fFN testing with CL measurement in the prediction of PTD.

Oral misoprostol or Foley catheter for induction of labour generates comparable costs.

(BJOG. 2017;124:453–461) An economic analysis of the previously reported HYPITAT-II study was undertaken to assess the relative costs of delivering a preterm fetus versus expectant monitoring in women with nonsevere hypertensive disorders of pregnancy. The HYPAT-II study included 703 pregnant women in the Netherlands between 34 and 37 weeks gestation with preterm nonsevere hypertensive disorders. They were randomly allocated to either immediate delivery upon diagnosis (n=352) or expectant monitoring of the mother and fetus (n=351). The HYPAT-II study found that expectant monitoring was the more clinically effective strategy as it resulted in significantly fewer cases of respiratory distress syndrome in the infant with a relatively small impact on maternal health. This current study was performed simultaneously with the HYPITAT-II trial with the goal of determining which of the 2 treatments was more cost effective.