Background and Objective:There were studies in the literature which showed the altered dermatoglyphics in the cleft children. But it would be beneficial if probable expression can be proved in prior generations, so that genetic counseling and other preventive measures can be undertaken. The aim of the study is to determine variations in dermatoglyphics of prior generations which would serve as bench markers to predict the occurrence of cleft in off springs.Materials and Methods:A total of 400 parents aged between 25-45 years were selected and divided into two groups - Group A consisted of parents with cleft children and Group B comprised of parents with at least 2 healthy children who met the inclusion criteria. Dermatoglyphic prints were collected by ink method and evaluated for pattern types, total ridge count and palm prints were evaluated for a-b ridge count, atd angle and asymmetry.Results:Significant difference was observed between Group A and B with reference to pattern types; TRC and a-b ridge count and atd angle. Absence of t point was variably noticed in the mothers of affected children.Conclusion:Dermatoglyphics can be used as tool to study the developmental instability of cleft anomalies and provides data to assess the genetic etiology of clefting.

A case of 42 years old male patient clinically suggestive of peritonitis due to appendicular perforation underwent exploratory laparotomy revealed normal appendix along with a large caecal perforation without any underlying primary or secondary pathologies. Caecostomy with Malecot's catheter with purse string sutures around the catheter was put in place. The suspicion of inadequate differential diagnosis later on revealed it as non specific caecal ulcer (NSCU) in the histopathology sample of perforated ulcer.

Cornual pregnancy is the most dangerous type of ectopic pregnancies but fortunately it occupies 2-4% of them. Its mortality rate is 6-7 times higher than that in all ectopic pregnancies. We reported a case of a uterine rupture in a 10 week cornual pregnancy.A 40 years old woman, gravida 2, para 1 was admitted to our emergency service with the complaint of an acute onset abdominal pain of about 6 hours duration. She was known to be in her 10th weeks of gestation after in-vitro fertilization (IVF) and embryo transfer. On examination, a severe degree of pallor, with a pulse of 104 bpm and a blood pressure of 70/40 mm of Hg was detected. Pelvic ultrasonography showed a thickened endometrium and an empty uterine cavity. In the right cornual fetus with a crown-rump length of 10 weeks of gestation was detected with a positive heart rate. The abdomen was filled with blood and blood clots. The haemoglobin level was detected as 5.8 g/dl. An emergency laparotomy was performed because of hemodynamic instability.Cornual pregnancies are very life threatening emergency conditions. Our case report demonstrates how a woman may come close to death while trying to have a child. To save lives of women generally immediate intervention instead of expectant management should be preferred as we did fortunately. So, more detailed examination by transvaginal ultrasonography guides the clinician for accurate diagnose before rupture occurs.