Acute Myocardial Infarction-Hunt and Sloma BRIISH i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MEDICA JOURNAL coronary artery in each case, and marked cardiac enlargement in seven out of eight men with persistent bundle-branch block who died within two months of their first infarction. When advanced surgical techniques become available to patients with acute myocardial infarction it is unlikely that any procedure -short of replacement of the heart will benefit patients with bundle-branch block because of the extensive infarction usually involving the septum, severe coronary artery disease, and evidence of cardiac hypertrophy.We wish to thank the physicians of the Royal Melbourne Hospital for permission to study cases under their care. REFERENCES Bauer, G. E., Julian, D. G., and Valentine, P. A. (1965 '., 1969, 1, 88-91 Summary: In a patient with giant-cell carcinoma of the lung a secondary tumour deposit in the arm was incised and bled for three weeks. Investigations showed the tumour to be rich in plasminogen activator. Haemostasis in the tumour was achieved with aminocaproic acid therapy. For a period the plasminogen-activator properties were retained in cell culture of the tumour.

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5 cases of true precocious puberty (TPP) of cerebral origin are presented. The clinical and radiological features and the protracted follow-up allow, also in view of the literature, a highly presumptive diagnosis of a hamartoma of the tuber cinereum. The high incidence of these lesions in cases of TPP is emphasized, together with the importance of early neuroradiological assessment.