The proposed delayed reservation decision scheme offers the same node complexity as that in general OBS networks with optical buffers. Simulations show the proposed scheme has better performance than existing schemes in terms of burst loss probability.

ABSTRACT. The interleukin-1α (IL-1α) gene appears to play a role in the pathogenesis of type 1 diabetes (T1D). Therefore, the aim of this study was to investigate the contribution of the IL-1 rs1800587 gene polymorphism to susceptibility to T1D in Chinese children. This casecontrol study included 332 Chinese children with T1D and 332 healthy controls. Identification of genetic variants of rs1800587 in the IL-1α gene was performed by polymerase chain reaction amplification. The IL-1α rs1800587 polymorphism demonstrated a significant association with T1D risk. The allelic frequency significantly differed between the T1D and control groups [odds ratio (OR) = 0.7; 95% confidence interval (CI) = 0.52-0.86; P = 0.002]. Furthermore, significant differences were observed in the dominant model (CC/CT + TT; OR = 0.6; 95%CI = 0.46-0.85; P = 0.003). In T1D patients, the prevalence of hypertension in T allele carriers was 4.2-fold higher than that in C allele carriers, (95%CI = 2.67-6.58; P < 0.001). In conclusion, the present study found evidence of a significant association between the rs1800587 polymorphism in the IL-1α gene and T1D.

We investigate two different node structures with fiber delay lines (FDLs) in optical burst switching networks: FDL share per node and FDL share per link. We study the roles of maximum delay and the single FDL element granularity in FDL share per node. Our simulations show that FDLs with limited delay can effectively improve the network performance in terms of burst loss probability, but increasing the maximum delay beyond a certain range or making FDL granularity much finer cannot improve network performance effectively. The performance improvements in different reservation schemes are also compared.