A prospective study was performed on an autopsy material consisting of 739 consecutive cases over 20 years of age (391 females, 348 males) during a period of six months. The material included about 70% of the deaths in the city of Malmö (approximately 250,000 inhabitants). The adrenals were specially observed at autopsy for adenomas and hospital records were searched for hypertension and diabetes mellitus. In the total material the frequency of adrenocortical adenomas was 8.7%, which was considerably higher than previously reported figures. In patients with essential hypertension the adenoma frequency was 12.4% as against 7.9% in normotensives. This difference was not statistically significant. The adenoma frequency in men with secondary hypertension was remarkably high but the significance is not clear. In patients with hypertension the frequency of diabetes was 17.6% as compared to 9.0% in normotensives. This difference was statistically probably significant. In patients with diabetes the frequency of adrenocortical adenomas was 16.5%, in non‐diabetics 7.7%. The difference was probably significant.

No abstract

No abstract

No abstract

Introduction Some patients with breast cancer develop local recurrence after breast-conservation surgery despite postoperative radiotherapy, whereas others remain free of local recurrence even in the absence of radiotherapy. As clinical parameters are insufficient for identifying these two groups of patients, we investigated whether gene expression profiling would add further information.