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This contribution proposes a study of the mechanical behavior from damage to fracture of normalized and annealed samples of AISI 4340 steel. Besides, a numerical study in a security device of offshore industry is conducted. Experimental tests were initially performed on smooth and notched cylindrical specimens subjected to monotonic tension as well as on rectangular specimens subjected to pure shear and a combination of shear and tension loads. Such experimental tests were selected to observe different combinations of the stress triaxiality and the normalized third invariant concerning the stress state. The two types of heat treatments were considered to achieve different levels of ductility and verify their influence on the fracture mode of the alloy. The approach based on the second invariant of the deviatoric stress tensor ( J 2), with nonlinear isotropic hardening, is assumed to describe the mechanical behavior of the material in axisymmetric and three-dimensional numerical simulations. Finite elements simulations were carried out to analyze the performance of a simplified version of a mechanism of a blow-out preventer-BOP valve. The experimental and numerical curves of force versus displacement were compared, highlighting the effect of the stress triaxiality, the third invariant and calibration condition on the behavior of the material. The evolution of the equivalent plastic strain was plotted, and the fracture onset compared with its maximum value. The results show that the AISI 4340 alloy is highly dependent on the stress triaxiality and third invariant. Moreover, it can be concluded that different calibration conditions for the isotropic hardening curve can result in different levels of forces for the correct performance of the BOP in a critical situation.