Present work comprises the use of different multivariate spectroscopic methods for tracking novel metabolomics signatures related to red wine chemistry. It is presented for the first time the proton nuclear magnetic resonance metabolomics fingerprint of a monovarietal Mexican Merlot, obtained with acquisition improvements recently proposed to the OIV Methods of Analysis sub-commission. Effective multi-presaturation solvent schemes have revealed a rich (poly)-phenolics aromatic region, so far not exploited for wine-fingerprinting or – targeted profiling routines. It is presented as well for the first time the use of simultaneous absorbance-transmission and fluorescence excitation-emission matrix “push-one-bottom” method (A-TEEMTM) at specific chemical conditions for a rapid, effective and high-sensitivity characterization of phenolic choreography in wines, as novel observables to quantify oenological practices and aging.

Facing climate change in wine industry comprises the implementation of strategies, such as to reduce alcohol in wines, promoted by abnormal increment of sugar levels in wine grapes. The present work discusses the first industrial-scale use of specific yeast strains able to produce wine with reduced alcoholic concentration. Reduction of alcohol content and quantification of key metabolites associated to oenological practice and/or quality were simultaneously measured in a “one-shot” way with proton Nuclear Magnetic Resonance Spectroscopy. Novel relevant metabolites were revealed with the use of a two-dimensional 1H-13C HSQC multipresat correlation spectroscopy, whereas a detailed methodological NMR description is stressed, towards revealing novel resonances within the NMR signature. The use of multitask analytical methods to simultaneously describe alcohol reduction and NMR targeting, completes the portfolio of NMR solutions recently proposed to the World Organisation of Vine and Wine for as well quantify aging and varieties.