An experiment was conducted to study the effect of irrigation and weed management practices weed seed bank at college farm situated in College of Agriculture, PJTSAU, Hyderabad, during kharif 2019 and 2020. The experiment consisted of two main plot treatments and nine subplot treatments laid out in Split plot design replicated thrice.  Two irrigation practices (Alternate wetting and drying irrigation and continuous submergence) and nine weed management practices (pretilachloar 50  EC 660 g ha-1(PE) fb mechanical weeding  twice, pyrazosulfuron ethyl + pretilachloar 6.15  GR 615 g ha-1 (PE) fb penoxsulam + cyhalofop p butyl 6.12  OD 125 g ha-1 (POE), orthosulfamuron + pretilachloar 6.6 GR 600 g ha-1 (PE) fb mechanical weeding twice, penoxsulam + butachloar 39.77 SE 820 g ha-1  (PE) fb mechanical weeding, flucetosulfuron 10% WG 25 g ha-1(Early PoE) fb mechanical weeding, bispyribac sodium + 2, 4-D sodium salt 56.3 SP 703.75 g ha-1  (PoE) fb mechanical weeding once, florpyrauxifen benzyl + cyhalofop p butyl 12  EC 150 g ha-1 (PoE) fb mechanical weeding once, hand weeding twice and unweeded control). There was no significant difference observed in irrigation practices for grain yield. With respect to weed managements, significantly higher grain yield was recorded in hand weeding and integrated weed management (IWM) involving penoxsulam + butachloar fb mechanical weeding. As an economics aspect is concerned, continuous submergence recorded higher cost of cultivation and higher grass return. Among weed management practices, hand weeding and IWM involving penoxsulam + butachloar fb mechanical weeding recorded higher cost of cultivation and higher gross return. As net return is concerned, IWM involving penoxsulam + butachloar fb mechanical weeding recorded higher, whereas B: C ratio in chemical weed control.