An apparatus is described which permits of efficient and simultaneous extraction of a large number of paper strips, as in use in paper electrophoresis. The fully automatic procedure reduces the amount of work required to a minimum.

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SummaryWe have constructed a fully automatic, self-recording and self-integrating strip photometer, which has been specially designed to analyze filter paper strips as obt~hdd by electrophoresis on filter paper, The quantitative analysis of the vaxlous protein fractions takes place while the curve is recorded, an accuracy being reached of about 0.5~o. w 1. Introduction. In connection with clinicochemical investigations the need was felt at our laboratory of an apparatus capable of automatic photometry of the paper strips obtained by means of paper electrophoresis 1)s). The apparatus should record a curve and simultaneously calculate the ratio of the various protein fractions. The requirements of such an instrument are great accuracy, moderate speed (max. 3 minutes per analysis) .mad the possibility of writing the curve on the back of cards (10 • 15 cm) to be filed in a card index. These requirements involve the use of a pen recorder coupled to a servomotor, the high precision making the heaviest demands on amplifier and integrator. Rapid stopping of the servomotor is of particular importance to avoid overshoot. The last requirement is that the instrument should stop automatically at the minima of the curve to permit readings of the ratios of the fractions. As will be seen below, we have succeeded in meeting all these demands. w 2. Mechanical and .ical pa,,t. The light from an incandescent lamp A (6 V, 0.9 A) falls via a condenser lens'B, a colour filter C and a cylinder lens D on a semipermeable mirror E (see fig. 1). Half---180 --