Pyridine derivatives with bridges Pyridine derivatives with bridges R 0460Synthesis and Stereochemistry of Some 3-Azabicyclo[3.3.1]nonane Derivatives.-Michael addition of various α,β-unsaturated carbonyl compounds to oxopiperidinecarboxylate (I) provides access to the title azabicyclononane derivatives as diastereomeric mixtures. The structure of adducts is studied in detail using NMR techniques.-(VAFINA, G. F.; YAKHINA, G. R.; KHAKIMOVA, T. V.; SPIRIKHIN, L. V.; GALIN, F. Z.; YUNUSOV, M. S.; Russ.

Reduction of 6-acetoxy-3-benzyl-1-ethoxycarbonyl-3-azabicyclo[3.3.1]nonan-9-one with sodium borohydride was investigated in various conditions. The stereochemistry of reduction products was deduces from 1 H and 13 C NMR and mass spectra.

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Chemistry of 3-Azabicyclo[3.3.1]nonane. Part 2. Reduction of 6-Acetoxy-3-benzyl-1-ethoxycarbonyl-3-azabicyclo[3.3.1]nonan-9-one withSodium Borohydride. -The stereoselectivity concerning the reduction of title compound (I) with sodium borohydride under variable conditions is studied. The ratio of αand β-epimeric alcohols is approximately 2:3 almost in all cases. -(VAFINA, G. F.; YAKHINA, G. R.; SPIRIKHIN, L. V.; GALIN, F. Z.; YUNUSOV, M. S.; Russ.