Rationale & Objective: Clinical practice guidelines for dietary intake in hemodialysis focus on individual nutrients. Little is known about associations of dietary patterns with survival. We evaluated the associations of dietary patterns with cardiovascular and all-cause mortality among adults treated by hemodialysis.
Background Fibromyalgia (FM) is a common condition in young and middle-aged women, which is mainly characterized by diffuse chronic pain and is associated with other manifestations such as fatigue, unrefreshing sleep, stiffness, anxiety and depresión1. Recent studies have evaluated that chronic pain syndrome and related manifestations could have a negative impact on sexual function of these patients, as well as psycho-physical abuse history could act as potential triggers of FM. Objectives Assess sexual function in women with FM and correlate with tender points count, clinical severity, anxiety, depression, chronic fatigue and history of physical and psychological violence. Methods A case-control study. Between 03/01/12 and 06/30/12 were included consecutively: women >18 years diagnosed with FM according to ACR criteria '90, and healthy controls >18 years, without history of violence. We excluded patients with other causes of chronic pain disorders and psychotic disorders. We recorded: sociodemographic data, education, employment and menopausal status and sexual function by Female Sexual Function Index2 (FSFI: self-administered questionnaire that assesses six domains: desire, arousal, lubrication, orgasm, satisfaction and pain). In the FM group tender points count, duration of disease, medication, psychological care, presence of chronic fatigue (by Fukuda Criteria), clinical severity (FIQ-Spanish version), depression (HADS), and history of physical or psychological violence (Screening Questionnaire of Violence) 3 were assessed. We used Chi2 test, Student t test and Mann-Whitney test, and Spearman correlation coefficient (significant p ≤ 0.05). Results We included 52 patients in the FM group and 52 in the control group. Median age: 50 ± 9.2 and 47 ± 10 years, respectively. FM Group: Medium evolution time: 60 months, mean pain points: 15 ± 3, FIQ median: 67.8 (28-86). 73.1% received medication for FM and 44.2% demanded psychological care. We found significant impaired sexual function vs controls (median FSFI total: 17.2 (1.2-33.3) vs. 29.4 (1.2-36), p <0.001) and the difference persists analyzing each domain of the FSFI. Patients with FM showed he most common link with the aggressor was, the current partner in cases of psychological violence (28.1%) and former partners for physical violence (31.25%). Having violence history showed a trend to lower values of FSFI (no statistical significance). No correlation was found between values of FSFI and the other analyzed variables. Conclusions Our patients with FM had impaired sexual function compared to control group. Physical and psychological violence were frequent but weren´t related with sexuality function. References Kalichman L. Association Between Sexual Dysfunction and FM. Clinical Rheum 2009, 28: 365-69. Blumel JE, Binfa LE, Cataldo PA, Carrasco AV. Female Sexual Function Index: a test to assess women’s sexuality. Rev Chil. Obstetrics Gynecol 2004; 69 (2): 118-125. Tavara-Orozco L, Zegarra-Samame Turra, Ceiso Zelaya. Screening Gender Violence: thr...
Background Rheumatoid arthritis (RA) is associated with increased cardiovascular mortality due to myocardial infarction, stroke and heart failure. Both, chronic inflammation leading to arterial stiffness, and some of the drugs used to treat RA, such as corticosteroids and leflunomide, are risk factors for developing arterial hypertension (HT). Objectives The aim of this study is to determine the prevalence of HT in outpatients with RA at a rheumatology office in Buenos Aires, and describe their relationship with clinical, laboratory and disease activity Methods We evaluated consecutive outpatients with a diagnosis of RA according ACR 90 criteria that attend to the Rheumatology office of a public hospital in Buenos Aires. Blood pressure (BP) was assessed by 3 protocolized measurements, clinical data was collected and disease activity was evaluated by DAS28-ESD. Statistical analysis was performed to establish prevalence of hypertension and to establish association with clinical and laboratory variables using Mann Whitney and Chi Square test. Significance was p≤0.05. Results We analyzed 99 patients (85.9% female and 14.1% male) with a mean age of 51.3 years old (range 26-80). 79.8% had Functional Class I and II. The prevalence of hypertension in our population was 50.5%. The median time to progression of RA: 9.57 years, DAS 28: 4.06 (range: 1.54 to 7.55), 65.7% of individuals take corticosteroids. HT was associated with age (56.16 years (26-80) the HT patients versus 46.35 years (26-81) for non HT patients(p <0.0001). The abdominal diameter was greater for the HT group (95.74 cm (92.31- 99.17) versus 90.59 cm (86.67 - 94.51) (p=0.035). The other analyzed variables don´t show statistical significance Conclusions Almost a half of RA patients had blood hypertension at the medical office during a standard control. It was significantly related to age and abdominal diameter. It was higher than the prevalence for the general population of Buenos Aires References Solomon D, Karlson E, Rimm E, Cannuscio C, Mandl M. Cardiovascular morbidity and mortality in women diagnosed with Rheumatoid arthritis. Circulation 2003;107:1303–7. Ferrante D, Virgolini M. Encuesta Nacional de Factores de Riesgo 2005: resultados prinicpales. Prevalencia de factores de riesgo de enfermedades cardiovasculares en la Argentina. Rev. Argent Cardiol. 2007; 75; 20-29. Hernandez- Hernandez R, Silva H, Velasco M, et al. Hypertension in seven Latin American cities: the cardiovascular Risk Factor Multiple Evaluation in Latin America (CARMELA) study. J. Hypertens 2010; 28; 24-34. Panoulas V, et. al. Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis. Rheumatology 2007;46:1477–1482 Disclosure of Interest None Declared
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