Summary The health status of 69 survivors of high-risk acute lymphoblastic leukaemia (ALL) is assessed using a multi-attribute classification system. Seven attributes are included: sensation, mobility, emotion, cognition, self-care, pain and fertility. Three to five levels of functioning are defined for each attribute. Comprehensive health states are described as a specific combination of seven attribute levels. The system captures combinations of sequelae. The system provides a compact but comprehensive tool for long term follow up of survivors of childhood cancer. The results underscore the cognitive and emotional burdens of morbidity affecting survivors of high-risk ALL.
A595influence the outcome of treatment. The objective was to assess patient preferences on treatments for ED by applying Conjoint Analysis. Methods: Seven attributes were selected through a literature review and a consultation with 25 patients treated of ED and 5 experts: effectiveness (E), rapidity of onset (R), duration of effect (D), adverse events (AE), methods of administration (MA), price (P) and interaction with alcohol and food (I). 3 groups of scenarios were selected using "Orthogonal Design": Phase 1, 9 scenarios with 4 attributes (R, D, MA, I); Phase 2, 16 scenarios with the 7 attributes; Phase 3, 9 scenarios with 4 attributes (E, MA, P, I). It was applied the "Order of simulated preference" method by using cards with symbols and text. Interactions of age, comorbidity and frequency of sexual intercourses with preferences were studied. Results: The set of 16 scenarios was very difficult for patients. A total of 314 patients participated in
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