Introduction: Burn is an injury to organic tissues as a result of thermal trauma. The use of tilapia skin as a biological dressing, which has been shown to be a promising, innovative and effective treatment for the treatment of extensive burns. Goal: To analyze the difference in the use of tilapia skin xenograft in burn healing, as well as the risk factors and final result. Method: Bibliographic review carried out from October to November 2022, using 12 articles in the PubMed database to compose the collection. Review: It is known that the lipid composition of tilapia skin acts positively as an immunoregulator, antimicrobial and scar modulator. Appropriate management is needed, both in skin removal and in sterilization and storage. Compared to the hydrofiber solution with silver, the use of Nile tilapia skin resulted in a decrease in pain and in the number of dressing changes, at the same time providing less possibility of infection. Therefore, it results in less use of pain medication, generating better recovery for the patient and less workload for the team. The tilapia xenograft presented limitations in the treatment of extensive burns and skin fold sites, being contraindicated in these cases. Conclusion:In view of its benefits, Nile tilapia skin can benefit patients with indication and public health systems due to its low cost and high effectiveness.

Goal: Discuss the prognosis of pituitary adenomas considering their clinical consequences and resulting systemic changes, in addition to possible therapeutic measures for management. Method: Literature review carried out from October to November 2022, through searches in the Scielo and Pubmed databases with the descriptors "pituitary adenoma", "symptoms", "treatment" and "diagnosis". 2925 articles were found and, after the inclusion criteria, 13 studies were selected. Review: Pituitary adenoma (HA) is the second most common intracranial tumor in the population. HAs can be asymptomatic, oligosymptomatic or cause clinical repercussions for the patient, ranging from visual disturbances to infertility. In this context, the diagnosis of HAs can be complex and must be performed by interdisciplinary professionals, with magnetic resonance imaging being the gold standard exam for imaging diagnosis. Final Considerations: There are variants regarding the tumorextension, pace of evolution and degree of impact on surrounding structures -that must be taken into account in order to shape an individualized and effective planning for each patient.

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