Gilbert's syndrome is a benign condition characterized by asymptomatic sporadic episodes of jaundice, due to a mild unconjugated hyperbilirubinemia caused by a deficiency in bilirubin glucoronidation. Under certain physiologic or pathologic events, bilirubin level rises but according to literature it does not reach out more than 3 mg/dl. We report 2 cases of Gilbert's syndrome, genetically tested, which presented with bilirubin levels above 6 mg/dl without any trigger or coexisting condition. In conclusion, bilirubin levels higher than 6 mg/dl in Gilbert syndrome are rare, hemolytic and other metabolism diseases must be ruled out, and genetic testing may be necessary in some cases.
married (p=0.008). No difference was found in post-operative length of stay, disposition, morbidity, 30-day mortality, or 30-day readmission rate. Pathologic evaluation of resected specimens showed no difference in margin status, lymph node positivity, perineural invasion, lymphovascular invasion, tumor grade, or degree of differentiation. AA had larger tumors than Caucasians (3.2 cm vs 2.5 cm; p =0.011). There was no difference in RFS between cohorts with 84% and 81% of AA and Caucasians still alive at 5 years, respectively. Median income and poverty were also analyzed. AA patients had a lower median income of $34,926 compared to Caucasians' of $51,449 (p= < 0.0001). Median of 25% of AA patients were in poverty compared to median of 14% of Caucasians (p = < 0.0001). Conclusion: While AA presented with larger tumors, we found no difference in post-operative outcomes or RFS compared to Caucasian counterparts. AA patients were more often single, have less income, and be under the poverty line compared to Caucasian counterparts as well. These data support that there are no differences in outcome based on race in this population based large cohort of patients.
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