Giant Condyloma acuminatum (GCA) , or Buschke-Lowenstein tumor (BLT), is a slow-growing, locally destructive, rare tumor that may occur in the anogenital region and it is related to human papillomavirus (HPV), which was first described by Buschke - Lowenstein in 1925. After consulting the databases of Latin American and Caribbean Literature (LILACS) and International Literature in Health Sciences and Biomedical (PubMed), without temporal delimitation or study design, using the MeSH terms "vulvar neoplasms," "giant condyloma of Buschke and Lowenstein", "condylomata acuminate”, we found 24 articles. After exclusion of the articles that did not address the BLT, it remained ten cases reported in the literature. We reported a case of BLT that clashes with the profile described in the literature. Consent was obtained from the patient for publication of the case and images.