Introduction: The non-traumatic subarachnoid hemorrhage (HSANT) remains with unchanged incidence rates, in contrast to the reduction in the occurrence of other cerebrovascular disorders. It shows high morbidity and mortality and causes disability in young people. Objective: to evaluate the clinical characteristics and treatment of non-traumatic HSA victims. Method: cross-sectional and descriptive study of 91 medical records from victims of non-traumatic HSA undergoing cerebral angiography in the Unified Health System (SUS) in Barbacena, between 2006 and 2010. Result: 55.0% of HSANT occurred in women; 48.3% between 31 and 50 years of age, with an average of 47 years old; explosive headache was the initial complaint in 84.6%; 71.2% hypertense and 65.9% due to aneurysm. Hydrocephalus was developed in 100% of patients undergoing surgery after the 16 th day after surgery; 100% of those infected remained hospitalized for more than six days. Conclusion: HSANT predominates in women between 31 and 50 years of age, having the explosive headache as the main complaint and aneurysmal disease as the main etiology. Hypertension was the major risk factor. The risk of infection is higher in patients admitted for more than six days, and the development of hydrocephalus seems to be associated with late surgical treatment.

Leprosy is a chronic infectious contagious disease caused by Mycobacterium leprae. Individuals with this comorbidity can be cured thanks to treatment with dapsone, clofazimine and rifampicin. The combination of drugs is known as multidrug therapy and the choice of combination depends on the classification of patients as paucibacillary or multibacillary. Rifampicin is part of standard treatment and renal anomalies secondary to its use are rare. However, the most common of these is acute renal failure. Because it is an unusual and potentially fatal side effect, it is necessary for health teams and patients to be alerted to the possibility of their occurrence, thus ensuring early detection of abnormalities and rapid management of side effects. We present a case of a patient with a diagnosis of dimorphic leprosy in treatment with multidrug therapy who developed acute renal failure after the tenth dose of rifampicin, requiring the suspension of the same.

Introduction: Hansen's disease is potentially disabling. It is an infectious and contagious chronic dermatosis caused by Mycobacterium leprae characterized by neurologic and cutaneous manifestations that can induce deformities and mutilations. Although curable, it is an important public health problem with increasing prevalence. Objective: to epidemiologically and clinically characterize leprosy in the macro-region of Barbacena-MG and determine the frequency and degree of physical incapacity of leprosy patients based on data collected in medical records. Method: this was a qualitative study based on the statistical description of medical records examined, paucibacillary (PB) and multibacillary (MB) comparison, and cross-sectional evaluation of 114 medical records of patients tended and recorded at SINAN. Results: among the reported cases of leprosy, 79.8% were MB and 20.2% PB, with an average age of 46.0 years, of predominantly male patients, with the dimorphic clinical form, with zero to five lesions, physical disability grade I, and with most evolving to cure. Comparisons between these groups showed statistical significance. Conclusion: multidisciplinary approaches are needed for Hansen's disease patients. Adherence to treatment combat the social stigma, reduces the incidence, and minimizes disease impact on the individual's life.

Direitos para esta edição cedidos à Atena Editora pelos autores. Open access publication by Atena Editora Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).