This paper analyses how technological and institutional innovation strategies were deployed towards achieving a high-scale, sustainable, knowledge intensive, locally grounded project, through the experience of an Argentinean biotechnology-based nutritional supplement delivered in schools to solve child malnutrition led diseases. The paper focuses on how the case of 'Yogurito' managed to address three challenges within recent Innovation for Inclusive Development literature: (1) involving heterogeneous actors in the innovation process within knowledge intensive technologies, (2) gaining scale while fostering participatory technology development processes, and (3) promoting the articulation of science, technology and innovation (STI) programmes with wider (social, sanitary and productive) policies. Through the trajectory of the probiotic yoghurt, the article examines learning and innovation strategies in technological design and institutional arrangements. We argue that the organizational strategies deployed to articulate scientific and locally grounded capacities were key elements that allowed the programme's working, its sustainability over time, and the unfolding of a regional development policy scheme.

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In this article we explore regulatory developments in stem cell medicine in seven jurisdictions: Japan, China, India, Argentina, Brazil, the USA and the European Union. We will show that the research methods, ethical standards and approval procedures for the market use of clinical stem cell interventions are undergoing an important process of global diversification. We will discuss the implications of this process for international harmonization and the conduct of multicountry clinical research collaborations. It will become clear that the increasing heterogeneity of research standards and regulations in the stem cell field presents a significant challenge to international clinical trial partnerships, especially with countries that diverge from the regulatory models that have been developed in the USA and the European Union.