ObjectiveTo provide national consensus and establish priorities with regards to the factors that promote the implementation and continued development of non-medical prescribing within health services.DesignClassic e-Delphi survey.SettingNational study in Wales.ParticipantsPharmacists, nurses and allied health professionals with the independent/supplementary prescribing qualification.ResultsA total of 55 non-medical prescribers agreed to become members of the expert panel of whom 42 (76%) completed the round 1 questionnaire, 40/42 (95%) completed round 2 and 34/40 (85%) responded to round 3. Twenty-one statements were developed, and consensus was achieved on nine factors representing those necessary for the successful implementation of non-medical prescribing and five representing actions required for its continued development. Strategic fit between non-medical prescribing and existing service provision, organisation preparedness, visible benefits, good managerial and team support, and a clear differentiation of roles were each important influences.ConclusionGiven the high degree of consensus, this list of factors and actions should provide guidance to managers and commissioners of services wishing to initiate or extend non-medical prescribing. This information should be considered internationally by other countries outside of the UK wishing to implement prescribing by non-medical healthcare professionals.