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The surface plasmon resonance (SPR) is a phenomenon based on the combination of quantum mechanics and electromagnetism, which leads to the creation of charge oscillations on a metal-dielectric interface. The SPR phenomenon creates a signal which measures refractive index change at the metal-dielectric interface. SPR-based sensors are being developed for real-time and label-free detection of water pollutants, toxins, disease biomarkers, etc., which are highly sensitive and selective. Smartphones provide hardware and software capability which can be incorporated into SPR sensors, enabling the possibility of economical and accurate on-site portable sensing. The camera, screen, and LED flashlight of the smartphone can be employed as components of the sensor. The current article explores the recent advances in smartphone-based SPR sensors by studying their principle, components, application, and signal processing. Furthermore, the general theoretical and practical aspects of SPR sensors are discussed.