MOlecular Database on Indian Insects (MODII) is an online database linking several databases like Insect Pest Info, Insect Barcode Information System (IBIn), Insect Whole Genome sequence, Other Genomic Resources of National Bureau of Agricultural Insect Resources (NBAIR), Whole Genome sequencing of Honey bee viruses, Insecticide resistance gene database and Genomic tools. This database was developed with a holistic approach for collecting information about phenomic and genomic information of agriculturally important insects. This insect resource database is available online for free at http://cib.res.in.Availability:http://cib.res.in/

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Sub-lethal baculoviral infections are associated with several developmental and reproductive defects but the mechanism behind these defects is not well understood. Here, we investigated the reproductive defects induced by sub-lethal infection of Spodoptera frugiperda nucleopolyhedrovirus (SfNPV) in Spodoptera frugiperda (J.E.Smith) adults. We observed significantly less oviposition, loss of fecundity and egg hatchability in surviving adults after SfNPV infection. Reciprocal crosses with both the genders suggested that the infection of either sex could result in the fertility defects. An investigation of anatomy of reproductive of the surviving females suggested minor defects but confirmed reduced mating with infected males. Oviposition defects were observed in the infected group in spite of successful mating. Differential transcriptome analysis of infertile females from sub-lethally infected group revealed alteration of reproductive, developmental and behavioural pathway genes in comparison to control. We have also investigated the involvement of hormonal genes and piRNAs in their contribution to reproductive defects post sub-lethal baculoviral infection. This study will shed some light on the molecular mechanisms behind the sub-lethal effects observed in the surviving adults post baculovirus infection and will be useful to understand the infertility pathways in insects.