As computer systems become more pervasive and complex, security is increasingly important. Secure Transmission refers to the transfer of data such as confidential or proprietary information over a secure channel. Many secure transmission methods require a type of encryption. Secure transmissions are put in place to prevent attacks such as ARP spoofing and general data loss. Hence, in order to provide a better security mechanism, in this paper we propose Enhanced Tiny Encryption Algorithm with Embedding (ETEA), a data hiding technique called steganography along with the technique of encryption (Cryptography). The advantage of ETEA is that it incorporates cryptography and steganography. The advantage proposed algorithm is that it hides the messages.

The multifold Sonogashira coupling of a class of aryl halides with arylacetylene in the presence of an equivalent of Cs 2 CO 3 has been accomplished using a combination of Pd(CH 3 CN) 2 Cl 2 (0.5 mol %) and cataCXium A (1 mol %) under copperfree and amine-free conditions in a readily available green solvent at room temperature. The protocol was used to transform several aryl halides and alkynes to the corresponding coupled products in good to excellent yields. The rate-determining step is likely to involve the oxidative addition of Ar-X. The green protocol provides access to various valuable polycyclic aromatic hydrocarbons (PAHs) with exciting photophysical properties. Among them, six tetraalkynylated anthracenes have been tested for their anticancer properties on the human triple-negative breast cancer (TNBC) cell line MDA-MB-231 and human dermal fibroblasts (HDFs). The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed to find out the IC 50 concentration and lethal dose. The compounds being intrinsically fluorescent, their cellular localization was checked by live cell fluorescence imaging. 4′,6-Diamidino-2-phenylindole (DAPI) and propidium iodide (PI) staining was performed to check apoptosis and necrosis, respectively. All of these studies have shown that anthracene and its derivatives can induce cell death via DNA damage and apoptosis.

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Plastics have become one of the most concerning pollutants today. They are non-biodegradable and potentially carcinogenic and lead to the generation of microplastics categorised as an emerging pollutant. Microplastics are plastic particles smaller than 5 microns in size. They are reported in various parts of the biosphere including human blood and tissues of various organs. Industrial and domestic effluents are two major contributing sources of microplastics in the ecosystem. A large volume of microplastics escape from the filtration processes of wastewater treatment plants (WWTP). This review studies the various removal methods for these pollutants in large-scale as well as lab-scale models and the present state of art facilities available to deal with it.

Adolescence represents a critical period for the programming of future adult behaviours. Neurogenesis is particularly active during adolescence, with increased number of granule cells and increased hippocampal volume both in animals and humans. Among the factors which can affect neurogenesis during adolescence, stress is considered a major one. Indeed, adolescence is known to be a particularly stressful period in life, with some adolescents suffering from mood disorders and anxiety. While there is increasing interest on the neurogenic changes occurring during the adolescent period, evidence is sparse. We conducted a systematic review summarising changes in hippocampal neurogenesis, neuroplasticity and hippocampal-dependent cognitive functions and behavioural outcomes in stress-induced adolescent animal models of depression, and investigating long-term stress effects on the same outcomes assessing the same animals in adulthood. Overall, the results show a significant reduction in hippocampal cell proliferation, and a concomitant increase in depressive-like behaviours in adolescent animals exposed to stress challenges, however reduction in the number of surviving neurons was accompanied by no changes in both cognition and behaviour. Studies also observed altered neuroplasticity, including a stress-induced decrease in markers of pre- and post-synaptic plasticity, dendritic spine length and density, and long-term potentiation. These changes in neuroplasticity were accompanied by cognitive impairments and depressive-like behaviours. Overall, some of the negative effects observed during adolescence, especially on cell proliferation, neuroplasticity, cognition and behaviour either persisted or worsened during adulthood. Interestingly, treatment during adolescence with antidepressants, glutamate receptor inhibitors, glucocorticoid antagonists, or a healthy diet consisting of omega-3 fatty acids and vitamin A, were able to reverse or prevent these detrimental effects. Future research should aim to investigate the translational impact of these preclinical findings, developing novel tools for the measurement of hippocampal neurogenesis directly in depressed adolescents, and subsequently assessing neurogenic changes in response to stress as well as pharmacological and non-pharmacological interventions.