Background: Various diagnostic methods have been developed to evaluate the palpable and non-palpable breast lesions, but Fine needle aspiration cytology of the palpable breast masses have become increasingly popular as a diagnostic technique to assess the breast lesions. To study the role of FNAC in diagnosis of breast lumps.Methods: 60 female patients (11-74 years age group) with palpable breast lump were utilized to study the role of Fine needle aspiration cytology for clinically palpable breast lump was carried out in Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh.Results: Fine needle aspiration cytology revealed benign in 22 patients, suspicious in 3 and 35 malignant lesions were 93.10% with false negative rate of 6.9% and false positive rate of 0%. The overall sensitivity of fine needle aspiration cytology in diagnosing the palpable breast lump in our study was 93.10%, specificity was 100%, positive predictive of 100% and negative predictive value of 90.47%.Conclusions: FNAC is easy to perform and painless procedure and standard tool for diagnosis of breast lumps with high percentage of true positives without virtual complications.

Background: Antibiotic prophylaxis can help to reduce surgical site infections in operative wound infections. Present work was done to study the use of antibiotic prophylaxis on operative wound infection.Methods: A total of 120 patients under went various surgeries in the department of surgery, Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh utilized for the present study. Out of 120 patients utilized 86 were males and 34 females with elective surgeries and observed from their admission to discharge from the hospital and also followed up all the patients up to fifth week of post-surgery. Surgical wound types were observed and recorded.Results: We have noted clean wound cases were 91, contaminated cases were 5 and clean contaminated were 24 noted. 11 infected cases were observed in clean wound type, 3 infected cases in clean contaminated were observed. 3 patients out of 120 patients had post-operative fever and subsided within 2 days without antibiotics. Out of 91 clean wound cases, 2 patients (2.19%) had post-operative fever, 10 patients (10.9%) developed with serous discharge and purulent discharge was developed in 1 (1.09%) case in present study. Bacteriology revealed 4 cases (4.29%) showed growth of staphylococcus aureus organism, 1 case (1.09%) with pseudomonas organism was noted. 2 cases (8.3%) developed with serous discharge and 1 case (4.16%) with purulent discharge and also growth of E. coli in 1 (4.16%) case was noted in 24 clean contaminated cases in present study.Conclusions: Use of antibiotic prophylaxis has a vital role in pre and post-operative wound infections.