A new species of Dracula (Pleurothallidinae: Orchidaceae) from Colombia is described, honoring Irmelin Indenbirken, mother of the actor and philanthropist Leonardo DiCaprio. D. irmelinae is phenotypically most similar to Dracula verticulosa, but differs in having larger and wider sepals that form a smoothly curved semicircular mentum behind the lip, an indumentum with dark red internal and external maculae and dense long pubescence on the internal sepal surfaces and bases of the tails. The geographic distributions of the two species also differ, with the new species being restricted to a small area in the western Cordillera of Colombia. The conservation status of the new taxon is assessed as Endangered (EN) according to the International Union for Conservation of Nature (IUCN) criteria. Key words: Colombia, Dracula, endangered species, Pleurothallidinae, Western Andes