Residual type B aortic dissection was numerically investigated to highlight the contribution of biomechanical parameters to the pathology's evolution. Patient-specific geometries from cases involving both favorable and unfavorable evolution were modeled to assess their hemodynamic features. This original approach was supported by a longitudinal study confirming the association between morphological changes, hemodynamic features, adverse clinical outcomes, and CT-angioscan observations on the same patient. Comparing one patient with unfavorable evolution with one with favorable one, we identify potential biomechanical indicators predictive of unfavorable evolution: (i) a patent false lumen with a flow rate above 50% of inlet flow rate; (ii) high wall shear stress above 18 Pa at entry tears, and above 10 Pa at some regions of the false lumen wall; (iii) low time-averaged wall shear stress in distal false lumen below 0.5 Pa; (iv) vortical structure dynamics. Although these comparisons could only be conducted on 2 patients and need to be confirmed by a larger number of cases, our findings point to these hemodynamic markers as possible candidates for early evaluation of the pathology's evolution towards an unfavorable scenario.
revascularization or the need of digestive resection did not significantly differ between sarcopenic and non-sarcopenic patients (10.5% vs 26.2%, P¼0.214 and 26.3% vs 47.5%, P¼0.118 respectively). The 30-day mortality did not significantly differ between the two groups (68.4% vs 55.7%, P¼0.427). The TPA/H was significantly negatively correlated with the neutrophil, thrombocyte and monocyte counts (r¼-0.283;-0.288,-0.225, P< 0.05) and positively correlated with the hemoglobin concentration and the glomerular filtration rate (r¼0.368; 0.261, P< 0.05). Conclusion: Further studies on longer follow-up period would be of interest to fully understand the prognostic value of sarcopenia in patients with acute mesenteric ischemia.
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