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At a Glance Commentary What is the current scientific knowledge on the subject? Currently there is no standardized, objective method for assessing symptom severity at exacerbation that has been universally accepted and available for use in both routine clinical practice and clinical trials. What does this study add to the field? The CAT provides a reliable score of exacerbation severity and its incorporation into assessment strategies may aid health care professionals to determine the severity of exacerbations and potentially assist management. The CAT may also prove useful in clinical trials to objectively assess the ability of novel interventions to reduce exacerbation severity.