Advancing research in medicine and technology has benefitted the mankind immensely with its contribution toward an improved life quality and increased life expectancy. The inability of a human body to autoregenerate has resulted in an increased demand for newer and healthier tissues and organs. Therefore, the restoration of naturally replicated tissue components has become a subject of interest for the scientific community lately. There was felt an intense quest for promoting strategies that could restore tissue regeneration and fuel the field of regenerative medicine. It was then the role of platelets was accounted for its wound healing and regenerative effects. Consequently, the use of platelet concentrates to improve wound healing, and bone formation was explored, which was considered to be possible because platelets contain high quantities of growth factors which would be able to stimulate cell proliferation, matrix remodeling, and angiogenesis, thereby establishing a new era of research with the successful application of innovative medical therapies focused on healing damaged tissues or regenerate the affected organs.

Aims and Objectives:The reverse pull headgear has been widely used to intercept a developing skeletal Class III malocclusion with maxillary deficiency. Rapid maxillary expansion (RME) is recommended along with the reverse pull headgear because there is disruption of the circummaxillary and intermaxillary sutures. This, in turn, expedites the orthopedic effect of the reverse pull headgear. However, studies have shown that the circummaxillary sutures may not be fully disrupted by the use of RME alone. The protocol of alternate RME and constriction (Alt-RAMEC) has been found to produce much more beneficial effects. Hence, this retrospective study was conducted to compare and assess the results obtained in the two methods.Materials and Methods:This study comprised pre- and post-treatment lateral cephalograms of two groups of nine patients each (total 18 patients – 10 females and 8 males) having skeletal Class III malocclusion (ANB<0°) due to a retrognathic maxilla with or without associated mandibular prognathism treated at the Department of Orthodontics of a teaching institute in Kerala. The patients were treated with either Alt-RAMEC/protraction or RME/protraction. The statistical analysis of the data was done using statistical package SPSS Version 16 software (SPSS Inc., Chicago, IL, USA).Results:Skeletal, dental, and soft-tissue parameters in Group 2 (Alt-RAMEC group) showed very significant changes with the maxilla moving forward, mandible rotating backward and downward, and proclination of the maxillary incisors when compared to Group 1.Conclusions:It may be concluded from the results of our study that the Alt-RAMEC protocol and reverse pull headgear might be more effective than conventional RME and the reverse pull headgear to correct a retruded maxilla in a developing skeletal Class III patient.

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This paper aims to develop an analytical method to predict the low-velocity impact response of simply supported stringer stiffened panels. Since the combination of stringer and panel provides aircraft structure with variable thicknesses, significant mathematical modelling is required to predict the transverse impact response of this type of designs. Within this analysis, the effect of variable stiffness distribution due to the stringer presence has been included. The performance of various layups is investigated to find the most suitable combination for panel-stringer laminate under impact loading. Analytical models were developed based on a spring-mass system to predict the dynamic behaviour of the striker-plate domain and, finally, determine the contact force history, which shows the main novelty of this research. Compared with Finite Element results, the model developed proved to successfully predict stringer stiffened composite panels' response with a range of layups and geometry designs under low-velocity impact loading conditions. The analytical results agree with the available data in the literature, and the error is less than 5%.

T loop is comparatively reliable for the frictionless mechanics for the space closure than the other loops evaluated in clinical use.