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Recent advances on Vision Transformer (ViT) and its improved variants have shown that self-attention-based networks surpass traditional Convolutional Neural Networks (CNNs) in most vision tasks. However, existing ViTs focus on the standard accuracy and computation cost, lacking the investigation of the intrinsic influence on model robustness and generalization. In this work, we conduct systematic evaluation on components of ViTs in terms of their impact on robustness to adversarial examples, common corruptions and distribution shifts. We find some components can be harmful to robustness. By using and combining robust components as building blocks of ViTs, we propose Robust Vision Transformer (RVT), which is a new vision transformer and has superior performance with strong robustness. We further propose two new plug-and-play techniques called positionaware attention scaling and patch-wise augmentation to augment our RVT, which we abbreviate as RVT * . The experimental results on ImageNet and six robustness benchmarks show the advanced robustness and generalization ability of RVT compared with previous ViTs and state-of-the-art CNNs. Furthermore, RVT-S * also achieves Top-1 rank on multiple robustness leaderboards including ImageNet-C and ImageNet-Sketch. The code will be available at https://git.io/Jswdk.Preprint. Under review.

Convolutional Neural Networks (CNNs) have advanced existing medical systems for automatic disease diagnosis. However, a threat to these systems arises that adversarial attacks make CNNs vulnerable. Inaccurate diagnosis results make a negative influence on human healthcare. There is a need to investigate potential adversarial attacks to robustify deep medical diagnosis systems. On the other side, there are several modalities of medical images (e.g., CT, fundus, and endoscopic image) of which each type is significantly different from others. It is more challenging to generate adversarial perturbations for different types of medical images. In this paper, we propose an image-based medical adversarial attack method to consistently produce adversarial perturbations on medical images. The objective function of our method consists of a loss deviation term and a loss stabilization term. The loss deviation term increases the divergence between the CNN prediction of an adversarial example and its ground truth label. Meanwhile, the loss stabilization term ensures similar CNN predictions of this example and its smoothed input. From the perspective of the whole iterations for perturbation generation, the proposed loss stabilization term exhaustively searches the perturbation space to smooth the single spot for local optimum escape. We further analyze the KL-divergence of the proposed loss function and find that the loss stabilization term makes the perturbations updated towards a fixed objective spot while deviating from the ground truth. This stabilization ensures the proposed medical attack effective for different types of medical images while producing perturbations in small variance. Experiments on several medical image analysis benchmarks including the recent COVID-19 dataset show the stability of the proposed method.

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The widespread conversion of synthetic receptors into luminescent sensors has been achieved via the use of fluorescent-indicator displacement assays (F-IDAs). Due to their rigid structures and efficient binding affinities, cucurbit[n]urils, combined with a variety of fluorescent guests, have gained extensive utilization in fluorescent-indicator displacement assays for sensing non-fluorescent or weakly fluorescent organic compounds (analytes) in a selective and specific manner. This mini-review summarizes recent advances in the design of cucurbit[n]uril-based fluorescent-indicator displacement assays and discusses the current challenges and future prospects in this area.