Objectives The focus of this triple-blind randomized study was to evaluate the mechanical properties, antibacterial effect, and in vivo biocompatibility of glass ionomer cements (GICs) modified with ethanolic extracts of propolis (EEP). Materials and Methods For biocompatibility tests, 135 male Wistar rats were used and divided into nine groups: Group C (control, polyethylene), Groups M, M10, M25, M50 (Meron; conventional, and modified with 10%, 25%, 50% EEP, respectively), Groups KC, KC10, KC25, KC50 (Ketac Cem; conventional, and modified with 10%, 25%, 50% EEP, respectively). The tissues were analyzed under an optical microscope for different cellular events in different time intervals. Shear bond strength test (SBST) on cementation of metal matrices (n = 10, per group), adhesive remnant index (ARI) in bovine incisors (n = 10, per group), and antibacterial properties by the agar diffusion test (n = 15, per group) were analyzed. Statistical Analysis Data were analyzed by Kruskal-Wallis test followed by Dunn, and one-way analysis of variance test followed by Tukey's test (p < 0.5). Results Morphological evaluation demonstrated intense inflammatory infiltrate in Groups M10 and KC10 in the time intervals of 7 (p = 0.001) and 15 (p = 0.006) days. Multinucleated giant cells were shown to be more present in Group M1, with statistical difference from Control and KC50 Groups in the time interval of 7 days (p = 0.033). The SBST showed no statistical significance among the groups (p > 0.05). Antibacterial property showed a statistically significant difference between Meron and Meron 50%-EEP Groups, and between Ketac and Ketac 50%-EPP Groups (p = 0.001). Conclusions The intensity of histological changes resulting from the cements was shown to be inversely proportional to the concentration of propolis added; Ketac 50%-EPP was the concentration that had the most favorable biocompatibility results. Addition of EEP to GIC did not negatively change the SBST and ARI. Antibacterial property demonstrated a concentration-dependent effect. AbstractKeywords ► propolis ► histocompatibility ► orthodontics ► glass ionomer cements
Background: The focus of this study was to evaluate the antimicrobial, mechanical properties and biocompatibility of glass ionomer (GICs) modified by Chlorhexidine (CHX). Material and Methods: For biocompatibility, 105 male Wistar rats were used, divided into 7 groups (n=15): Group C (Control,Polyethylene), Groups M, M10, M18, and Groups RL, RL10, RL18 (M-Meron and RL-Riva Luting: conventional, and modified with 10%, and 18% CHX, respectively). The tissues were analyzed under optical microscope for different cellular events and time intervals. Antibacterial effect and Shear Bond Strength Test (SBST) were also analyzed. Biocompatibility was analyzed by the Kruskal-Wallis and Dunn tests; SBST one-way ANOVA and Tukey test (P<0.05). For the antibacterial effect, the Kruskal-Wallis and Friedman, followed by Dunn (P<0.05) tests were used. Results: Morphological study of the tissues showed inflammatory infiltrate with significant differences between Groups C and RL18, in the time intervals of 7(P=0.013) and 15(P=0.032) days. The antimicrobial effects of the cements was shown to be CHX concentration-dependent (P=0.001). The SBST showed no significant difference between the Groups of Meron cement (P=0.385), however, there was difference between Group RL and Groups RL10 and RL18 (P=0.001). Conclusions: The addition of CHX did not negatively influence the SBST. Meron-CHX-10% was the most biocompatible, and Riva-CHX-18% had more influence on the inflammatory process and presented slower tissue repair.
O estudo teve como objetivo identificar o perfil sociodemográfico dos estudantes do último ano de Odontologia da Universidade Estadual da Paraíba (UEPB) em 2016, os motivos que os levaram a optar pela Odontologia, a satisfação com o curso, bem como suas perspectivas de trabalho e de pós-graduação. A amostra foi constituída por 60 estudantes, que responderam a um questionário semiestruturado dividido em três blocos: perfil sociodemográfico; curso de graduação em Odontologia; e perspectivas de atuação profissional e de pós-graduação. Os resultados mostraram um predomínio de mulheres, jovens, solteiras, sem filhos, naturais do estado da Paraíba, com renda familiar mensal de 3 a 5 salários mínimos e sem familiares atuando como cirurgiões-dentistas. Seus pais apresentavam ensino médio ou superior completos e estavam inseridos no mercado de trabalho. Mais de 90% mostrou-se satisfeito com a opção pela Odontologia. Os motivos que os levaram a optar pela profissão foram a realização pessoal e profissional, seguida pelo interesse em atuar na comunidade. Cerca de 40% dos estudantes referiram reprovação e poucos referiram trancamento de matrícula no curso por algum período. Cerca de 80% dos estudantes avaliaram o curso como bom ou ótimo e consideram adequado o tempo de graduação de cinco anos. Pretendem trabalhar tanto no serviço público quanto no privado e fazer pós-graduação. Os achados permitiram identificar o perfil do formando em Odontologia da UEPB em 2016. Recomenda-se o acompanhamento permanente dos formandos como um importante instrumento de monitoramento de seu perfil e do desenvolvimento do currículo.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.