The principles of high-speed pre-fabricated industrial construction in the conditions of Northern regions are as follows. There are several types of methods for using industrial unified structures pre-fabricated at the factory in the form of light-weight multi-layer sandwich panels and aggregated block-modules. They are: complex mechanization of assembly processes, transportation and sequenced-flow organization of assembly on the basis of supplying aggregated sandwich panels. Key importance belongs to the following: adaptability of project solutions to streamlined production, accuracy of assembly and regular pace of assembly operations in the construction site by means of transportable small-size equipment.