Objective
The purpose of this systematic review and meta‐analysis was to determine the effect of nerve transfer surgery for brachial plexus injury (BPI) on patient‐reported outcomes.
Literature Survey
MEDLINE, EMBASE, and CINAHL were searched and screened in duplicate for relevant studies on September 25, 2019 and repeated June 24, 2020.
Methodology
The patient population included male and female patients who received nerve transfer surgery for BPI. Further inclusion criteria were: (1) all levels of evidence; (2) published in English; (3) conducted in humans; and (4) report of patient‐reported outcome. Two reviewers independently abstracted data regarding injury type, surgical technique, surgical timing, follow‐up duration, strength, and patient‐reported outcome measures. Quality was assessed in duplicate using the Methodological Index for Non‐Randomized Studies criteria.
Synthesis
Twenty‐one studies involving 464 participants were included in analyses. The mean age ± SD was 32.4 ± 1.8 (range: 5–77) and 89.2% of included participants were male. The mean time to surgery was 5.6 ± 0.6 months and the mean follow‐up time was 48.1 ± 8.4 months. The most used patient‐reported outcome was the Disabilities of Arm, Shoulder and Hand (DASH), where scores variably improved postoperatively, although the degree of disability remained high. Return to work was reported in five studies, with 66.0% of participants returning to work. Patient satisfaction was assessed in four studies with an overall satisfaction proportion of 64.0%. Pain was assessed in 12 studies using various measures. In studies reporting pain intensity postoperatively, 29.3% of patients were “pain‐free” or had “no pain.”
Conclusions
Patient‐reported outcomes following nerve transfer for BPI are infrequently reported in the literature. Although patient‐reported outcomes demonstrate variable postoperative improvement, there is evidence of ongoing limitations and postoperative DASH scores report a high degree of ongoing disability. Future studies with greater reporting as well as validation of patient‐reported outcomes within BPI are warranted.
This case report highlights the problems in diagnosing an acute lumbar disc prolapse in an 18-month-old child and reviews the current literature dealing with an acute disc prolapse in very young children.
Spasticity causes an array of disabilities, which in turn may lead to the need for surgical intervention. Spasticity itself may also negatively affect surgical outcomes. This report reviews the potential benefit of perioperative (before, during, or after surgery) botulinum toxin (BoNT) injections for 3 patients with spasticity due to spinal cord injury, stroke, or multiple sclerosis. We discuss perioperative BoNT in 3 time periods: preoperatively, intraoperatively, and postoperatively. The cases demonstrate the use of perioperative BoNT in decreasing pain, improving wound healing, and improving surgical outcomes. We conclude by discussing the potential use of perioperative BoNT for surgical interventions in patients with spasticity and the need for further high-quality research in this field.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.