Conclusions: Nonwhite CLTI patients have higher likelihood of MALEs compared with their white race counterparts despite similar rates of medical optimization by statin and antiplatelet use. Additional research should focus on individual, modifiable risk factors contributing to disparities in outcomes in efforts to improve outcomes for nonwhite CTLI patients.Objective: Peripheral artery disease is primarily an atherosclerotic process leading to an obstructive disease; its risk factors include hypertension, diabetes, hyperlipidemia, and smoking. Many patients experience a plethora of symptoms, including intermittent claudication, rest pain, and tissue loss, leading to a decreased quality of life. This is most commonly due to atherosclerosis of the superficial femoral artery. Endovascular approaches such as nonstenting balloon angioplasty (percutaneous transluminal angioplasty [PTA]) and stenting angioplasty (stent) have provided minimally invasive options for revascularization. The emergence of drug-eluting balloon (DEB) angioplasty has shown promising
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