Glycosaminoglycan (GAG) is a chain-like disaccharide that is linked to a polypeptide core to connect two collagen fibrils/fibers and provide the intermolecular force in a Collagen-GAG matrix which can be a valuable treatment of post-burn contractures and hypertrophic scars, which remain a challenge to reconstructive surgery. The face and neck contractures are the most difficult sites to treat. This article is meant to discuss our clinical experience in using collagen-glycosaminoglycan biodegradable matrix (Integra® Integra Lifesciences Corporation, Plainsboro, NJ, USA) to reconstruct defects created by excision of contracted areas from the neck and lower face areas. Between 2009 and 2011, we had 11 patients that underwent Integra reconstructive procedures. The mean follow-up period was 18 months. For all the patients, the intake of the Integra dermal regeneration template was 100%, even if one patient developed a minor infection treated with appropriate antibiotics. The patients are very satisfied with the result. A minor problem was a small difference in skin color, but this inconvenience was compensated by good skin elasticity.
The special clinical aspect of Dupuytren's disease is characterized by thickening and contracture of the fibrous pretendinous bands on the palmar surface of the hand and fingers. There are also presented firm nodules and atrophic grooves or pits in the pits in the skin of the palm of the hand. We analyzed the frequency of location of the contracture of the fibrous pretendinous bands, on one consecutive series of 200 cases. Only 2.5% of the cases were female. The bilaterality of Dupuytren's disease was evident in 53% of the cases. 26.5% of single affected hands were right and 20.5% were left. A percent of 73.5% of cases showed only one fibrous pretendinous band; 26.5% of cases showed association of two or three fibrous pretendinous band. The whole study material revealed the location of the fibrous pretendinous band as follows: 0.5% thumb; 1% index finger;15% middle finger; 87% ring finger and 25.5% little finger. The most common combination of affected fingers are in: 16.5% ring finger and little finger; 75% middle finger and ring finger; 2.5% middle finger, ring finger and little finger; 0.5% thumb and index finger. These data are important for the hand surgery. (Supported by CNMP 62054/2008).
The main traumatic deformities of the extensor expansion (EE) are the boutonnière lesion (BL) and the mallet finger (MF). The classical BL is characterized by flexion deformity at the proximal interphalangeal joint, with hyperextension of the metacarpophalangeal and terminal interphalangeal joint, caused by the rupture or division of the central slip of the EE in a finger. The MF is defined as a deformity resulting from loss of EE continuity to the distal finger joint. We analyzed the frequency of location for the two hands and for fingers II–V, on 2 consecutive series of 100 cases each. We noticed a slight predominance in the right hand fingers for both types of lesions: 54% for BL, and 57% for MF. Location of BL was as follows: 8% index finger (II); 42% middle finger (III); 29% ring finger (IV) and 21% little finger (V). There was no multidigital involvement in cases of traumatic BL. Location of MF was as follows: 34% index finger (II); 23% middle finger (III); 17% ring finger (IV) and 26% little finger (V). In three clinical cases there were two fingers involved (fingers IV and V). Traumatic lesions of the EE are more frequent in the dominant hand. The BL involve most often the fingers II and III (index and middle fingers), and MF lesions are more often located in fingers III and IV (middle and ring fingers). (Supported by CNMP 62054/2008).
The group of small hepatic veins form the lower group of hepatic veins ‐ participating in the venous drainage (VD) of the caudate lobe (CL) ‐ and the lower portions of right and left hepatic lobes. VDCL was examined by a number of 150 hepatic corrosion casts; the pieces were made by injecting plastic mass in the vascularductal elements of the liver, followed by corrosion of the parenchyma with hydrochloric acid. The number of the CL veins varies from four to fifteen (average of 8.77 veins/piece). The analysis of VDCL depending collector hepatic veins (HV) demonstrates that: the left HV participates in VDCL 17.33% by the tail vein 1.3 (mean 1.80 veins/piece); the middle HV participates in VDCL 100% through the tail vein 4.8 (mean 5.2 veins/piece); the common trunk formed from the middle and left HV participates in the VDCL as a percentage of 11.11%; the right superior HV participates in VDCL as a percentage of 62.67% through the tail vein 2.4 (mean 2.75 veins/piece); the right inferior HV participates in VDCL as a percentage of 12% CL by the tail vein 1.3 (mean 2.22 veins/piece); the Inferior Vena Cava (IVC) venous drainage involved in the CL in 100% of cases, 1.4 veins (veins averaging 1.77 veine/piece). CL main venous drainage is done mainly to the Middle Hepatic Vein (98.46% of the parts) and to the retrohepatic portion of the IVC (84.09%) (Supported by CNMP 41092/2007).
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