We present the case of T.F., a 28-year-old woman diagnosed with corpus callosum dysgenesis and colpocephaly. The diagnosis is based on cerebral imaging – magnetic resonance imaging (MRI) and computerised tomography (CT).

Cavernomas are frequent low-flow vascular malformations with a characteristic MRI aspect due to their specific morphology. We present the case of a 64-year old male diagnosed in 2008 with multiple cerebral cavernomas and symptomatic epilepsy, who developed left face, arm and leg paresthesia during the last 6 days. The MRI examination performed in our clinic showed increased number of infracentimetic lesions with no signs of hemorrhage or growth of the previous documented ones. Considering MRI findings and the patient being seizure free for the last three years there is no current indication for invasive treatment. The presence of multiple lesions along with their aspect on T2* MRI sequences suggest a hereditary form in absence of familial history of cerebral cavernous malformations.

The possibility of myasthenia gravis must be considered in patients persistently complaining of weakness and fatigue. There may be many difficulties and pitfalls in differentiating myasthenia gravis from other disorders in which muscular weakness is a common complaint. Myasthenia gravis is an autoimmune disease caused by a defect of neuromuscular transmission due to antibody mediated attack. Dysphagia and dysarthria are two of the common symptoms and are due to oropharyngeal muscles involvement. They can be the first symptoms of the disease and sometimes can be mistaken for manifestations of emotional problems, usually anxiety or depression. The disease may be underappreciated as a cause of bulbar weakness. If clinical findings and history are highly suggestive, complementary tests should be performed (and sometimes maybe repeated) in order to confirm the diagnosis before psychasthenia or another psychiatric diagnosis is considered. We report the case of a 42-year-old woman who was admitted in our clinic for swallowing difficulties leading at the end of the day to total dysphagia, dysarthria, fluctuating limb muscle weakness and bilateral eyelids ptosis with incomplete occlusion.

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We present the case of a 60 year-old woman diagnosed with meningiomatosis (multiple sporadic meningiomas), in the absence of neurofibromatosis type 2. The cerebral computerized axial tomography (CT scan) revealed six expansive lesions (one isodense and five spontaneously hyperdense partially or completely calcified), which at the cerebral magnetic resonance imaging (MRI) examination showed typical features of meningiomas. Case particularity: the very low incidence of sporadic multiple meningiomas and a rare cause of secondary epilepsy.