the effect of socio-economic deprivation by comparing survival in the most and least deprived groups in the transplanted and not listed groups. A significance level of p<0.05 was used with the Log rank test.Deprivation was assessed using the Scottish Index of Multiple Deprivation (SIMD) and groups were paired for analysis (group 1 most deprived; group 5 least deprived) Results When including all patients those transplanted (n=562; 103 deaths) had a significantly better survival than those not listed (n=230; 139 deaths) (Mean survival 2219 days (95% CI 1912-2526) vs. mean survival 645 days (95% CI 563-726). (Log rank p<0.001).There was no difference in survival when comparing the most deprived to the least deprived (SIMD 1 (n=84; 56 deaths) vs. SIMD 5 (n=32; 16 deaths)) in those patients not listed for transplant. (Mean survival 658 days (95% CI 474-842) vs. mean survival 680 days (95% CI 367-994). (Log rank p=0.969).When comparing survival in the most deprived (n=133; 32 deaths) to the least deprived (n=86; 13 deaths) in those patients that were transplanted, patients from the more deprived areas had a poorer survival. (Mean survival 1373 days (95% CI 1027-1719) vs. mean survival 1998 days (95% CI 1596-2400) (Log rank p=0.046).(Figure 1). Conclusions Overall liver transplantation gives a significant survival advantage compared to those not listed. Patients from more affluent areas of Scotland have improved survival to those from less affluent areas when transplanted. No difference is seen in those patients not transplanted.
Background
Previous studies recommend a resect and discard strategy for small, non‐cancerous colorectal polyps without histological examination, serving to reduce procedural time and screening costs. As surveillance protocols depend on the type of identified polyps, such an approach necessitates adequate endoscopic identification skills.
Methods
We assessed the applicability of this approach through a retrospective study in a UK secondary‐care center. We reviewed the accuracy of identification of colorectal polyps by comparing the endoscopic Kudo polyp evaluation from the procedure reports to the subsequent histological outcome.
Results
In 3,060 colonoscopies, 2,487 polyps were detected and 1,041 were included in the study and reviewed against their histology. Polyps were correctly classified as adenomas and hyperplastic in 84.1% and 66.4% respectively. With regards to adenomas, the likelihood of correct endoscopic diagnosis of Kudo IIIL (92.47%) and IV (93.94%) was significantly higher compared to the Kudo IIIS polyps (74.57%), P < 0.001. Correct identification rate was more likely for expert endoscopists (P = 0.04), whereas there was no statistical difference between different specialty groups (P = 0.59), endoscopists’ grade (P = 0.93), buscopan use (P = 0.83) and quality of bowel preparation (P = 0.54). Regarding hyperplastic polyps, the only factor associated with higher likelihood of correct classification was the timing of the procedure (P = 0.003). Fifteen per cent of the misclassified hyperplastic polyps were sessile serrated lesions.
Conclusion
Discard strategy could be feasible for sub‐centimetre polyps of Kudo type IIIL and IV, for endoscopists achieving a recommended ≥ 90% agreement with the histopathology findings. We suggest that all Kudo II and IIIS polyps are sent for histological assessment.
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