Purpose: To investigate the role of Helicobacter pylori in primary open-angle glaucoma (POAG) pathophysiology by detecting its presence in eye biopsies of POAG patients during trabeculectomy. Patients and Methods: Fifty-one consecutive patients who underwent trabeculectomy for POAG not responsive to antiglaucoma therapy, and 35 consecutive anemic controls were examined for H. pylori presence mainly by gastric mucosa histology. In POAG patients, eye biopsies were also obtained and stained for H. pylori presence in situ. Results: Forty-three of 51 (84.3%) POAG patients and 17 of 35 (48.6%) controls were tested H. pylori positive (p = 0.0004). In 5 H. pylori-positive POAG patients, H. pylori bacteria were identified in the trabeculum and iris specimens. Conclusion: For the first time, H. pylori bacteria have been detected histologically in eye biopsies of POAG patients.

Patients with exfoliation who had ECCE and posterior chamber IOL implantation had an increased risk of intraoperative complications. In these patients, surgery must be done by experienced surgeons able to handle all possible complications.

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Extracapsular cataract extraction in patients with Fuchs' heterochromic iridocyclitis does not currently present any difficulties compared with normal senile cataract. No major complications occurred and the final visual acuity was satisfactory.