(1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial prescribing trends among patients in public hospitals in Makkah hospitals. (2) Method: We undertook a point prevalence survey (PPS) in six hospitals in Makkah, Saudi Arabia, from January 2019 to July 2019. The survey included all the inpatients receiving antimicrobials on the day of PPS. Data was collected using the Global point prevalence survey (PPS) tool developed by the University of Antwerp, Belgium. (3) Results: Of 710 hospitalized patients, 447 patients (61.9%) were treated with one or more antimicrobials during the study period. The average bed occupancy among six hospitals was 74.4%. The majority of patients received antimicrobials parenterally (90.3%). Of the total prescribed antimicrobials, 415 (53.7%) antimicrobials were used in medical departments, 183 (23.7%) in surgical departments, and 175 (22.6%) in ICUs. Pneumonia (17.3%), skin and soft tissue infections (10.9%), and sepsis (6.6.%) were three common clinical indications. Ceftriaxones were the most commonly used antibiotics that were prescribed in 116 (15%) of patients, followed by piperacillin, with an enzyme inhibitor in 84 (10.9%). (4) Conclusion: There was a high prevalence of antibiotic use in the hospitals of Makkah, which could be a potential risk factor for the incidence of resistant strains, particularly MRSA infection. Public health decision-makers should take these findings into consideration to update national policies for antibiotic use in order to reduce the risks of further increases of AMR.

Introduction: In general practice, approximately two-thirds of antibiotic prescriptions are for respiratory tract infections. Acute respiratory tract infections, which include acute uncomplicated bronchitis, pharyngitis, rhinosinusitis and the common cold, are often common reasons for acute outpatient visits to physicians and antibiotic prescriptions for adults. The improper treatment of acute respiratory tract infections is now an urgent public health threat, as it is an important contributor to antibiotic resistance. In developing countries, including Saudi Arabia, antibiotics are prescribed excessively and are often obtained without prescription. Aim: The aim of this study was to gather information on current antibiotic prescribing rates for respiratory tract infection in Hera General Hospital Makkah Almukarramah, Saudi Arabia. Method: A cross-sectional study, incorporating systematic sampling on clinical data from antibiotic prescriptions in hospitalised and emergency departments at Hera General Hospital, was conducted. From September 2017 to April 2018, approximately 500 prescriptions were collected from each hospitalised and emergency pharmacy for patients with respiratory tract infections. Results: The most prescribed antibiotics for respiratory tract infections came from the penicillin group and ciprofloxacin. The prescribing of antibiotics for respiratory tract infections was more prevalent amongst males than females. Potential over-prescribing of antibiotics for upper respiratory tract infections specially patients with otitis media especially in children without proper lab investigations.

Objectives: To demonstrate the adult standardized concentration of Antibiotics intravenous infusion as new initiatives in the Kingdom of Saudi Arabia. Methods: It is a new initiative project drove by national standardized concentration of Antibiotics services. The projects formulated from the international business model, pharmacy project guidelines and project management institution guidelines of a new project. The initiative project is written through project management professionals and contained of several parts, including the initial phase, the planning phase, the execution phase, the monitoring and controlling phase. Results: The adult standardized concentration of Antibiotics intravenous infusion services with a defined vision, mission and goals. The services had various benefits including clinical and economic on patients as exemplified in the review. The continuous of the project assured by risk management model description. In addition, the monitoring and controlling of the services as declared. The transition to operation project though closing project stage was explored in the analysis. Conclusion: The adult standardized concentration of Antibiotics intravenous infusion services is a new initiative part of the intravenous admixture program. The standardized concentration of Antibiotics will lessening drug-related problems and improve patient safety at hospital practice; it is highly recommended to implement in the Kingdom of Saudi Arabia.

Background: Hospitalized pediatrics, especially neonates, are more prone to excessive medication errors. Implementation of pharmacy services shows a decline in medication errors in hospitals and clinics. In this study, we aimed to demonstrate the role of pharmacists in reducing medication errors in hospitalized neonates Methods: The systematic review of the literature was undertaken through the PubMed database from 2002 to 2022. The search MESH terms were multiple combinations of Medication error, Clinical pharmacist, Clinical pharmacy services, Infant & newborn. Afterward, the results were filtered to include the role of pharmacy services in preventing medication errors for the inpatient neonatal population Results: a total of 15 articles were eligible to be included in the current review, comprising neonatal or whole pediatric population, including neonates. The primary pharmacy interventions were prescription auditing, identification of medication errors, changing preparation and administration, medication reconciliation, educating healthcare workers, and developing policies Conclusions: Our systematic review illustrated that pharmacists integration with other healthcare teams could help minimize medication errors before reaching neonates.