BACKGROUND: Meningiomas are the most common primary benign brain tumors in adults. Given the extended life expectancy of most meningiomas, consideration of quality of life (QOL) is important when selecting the optimal management strategy. There is currently a dearth of meningioma-specific QOL tools in the literature. OBJECTIVE: In this systematic review, we analyze the prevailing themes and propose toward building a meningioma-specific QOL assessment tool. METHODS: A systematic search was conducted, and only original studies based on adult patients were considered. QOL tools used in the various studies were analyzed for identification of prevailing themes in the qualitative analysis. The quality of the studies was also assessed. RESULTS: Sixteen articles met all inclusion criteria. Fifteen different QOL assessment tools assessed social and physical functioning, psychological, and emotional well-being. Patient perceptions and support networks had a major impact on QOL scores. Surgery negatively affected social functioning in younger patients, while radiation therapy had a variable impact. Any intervention appeared to have a greater negative impact on physical functioning compared to observation. CONCLUSION: Younger patients with meningiomas appear to be more vulnerable within social and physical functioning domains. All of these findings must be interpreted with great caution due to great clinical heterogeneity, limited generalizability, and risk of bias. For meningioma patients, the ideal QOL questionnaire would present outcomes that can be easily measured, presented, and compared across studies. Existing scales can be the foundation upon which a comprehensive, standard, and simple meningioma-specific survey can be prospectively developed and validated.
Executive dysfunction is a hallmark of traumatic brain injury (TBI) and is associated with significant complications. Deficiency in problem-solving, emotion regulation, and attention is one of the most common phenomena after brain injury. This study aimed to evaluate the effectiveness of shortterm intervention of dual executive function on problem-solving, emotion regulation, and selective attention in patients with traumatic brain injury. This quasi-experimental design used pre-test and post-test with a control group. Twenty subjects with brain injury were selected with the Purposive sampling method. They were randomly entered into two experimental and control groups (10 in the experimental group and 10 in the control group). After performing the pre-test, the experimental group received the short-term intervention and double executive function in 8 sessions of 90 minutes, while the control group did not receive any intervention. The assessment was performed in two stages of pre-test-post-test using a set of software tests of the Tower of London, Stroop and John and Gross (2003) Emotion Regulation Questionnaire. Analysis of covariance was used to analyze the data. The results showed a significant difference in the mean scores between the experimental group and the control group in all variables after the test. Therefore, it can be concluded that short-term intervention of dual executive function has a significant effect on improving attention, emotion regulation, and problem-solving in people with traumatic brain injury.
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