Recently, an outbreak of a novel human coronavirus which is referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (COVID-19) by the World Health Organization (WHO) was identified in Wuhan, China. To help combat the pandemic, a systematic review (SR) was performed to collect all available studies concerning inactivation methods, environmental survival, and control and prevention strategies. A comprehensive literature survey yielded 42 eligible studies which included in the SR. The results confirmed that the WHO recommended two alcohol-based hand rub formulations (ethanol 70-95% and 2-propanol 70-100%) had an efficient virucidal activity in less than 60 s by more and equal 4 log 10 (≥ 99.99) approximately and could be used for disinfection in public health and health-care facilities. The findings indicated that SARS-CoV-1 and SARS-CoV-2 can survive under different environmental conditions between 4 and 72 h approximately. The results also demonstrate that temperature and relative humidity are important factors in the survival of SARS-CoV-2. The main strategies recommended by the WHO to avoid contracting SARS-CoV-2 are hand washing several times in the day and maintaining social distancing with others. It is important to note that the more studies require addressing, the more possible airborne transmission due to the survival of SARS-CoV-2 in aerosols for 3 h approximately. We hope that the results of the present SR can help researchers, health decision-makers, policy-makers, and people for understanding and taking the proper behavior to control and prevent further spread of SARS-CoV-2.

Prebiotic-supplemented and regular formula were similar to breast milk regarding prophylactic effects for diarrhoea, constipation and respiratory tract infections in the first year of life. Prebiotic-supplemented formula may be an appropriate substitution for breast milk when breast milk in unavailable.

Background:Peptic ulcer is a prevalent problem and symptoms include epigastria pain and heartburn. This study aimed at investigating the prevalence and causes of peptic ulcers in Iran using systematic review and meta-analysis.Materials and Methods:Eleven Iranian papers published from 2002 to 2016 are selected using valid keywords in the SID, Goggle scholar, PubMed and Elsevier databases. Results of studies pooled using random effects model in meta-analysis. The heterogeneity of the sample was checked using Q test and I2 index.Results:Total sample size in this study consist of 1335 individuals with peptic ulcer (121 samples per article). The prevalence of peptic ulcers was estimated 34% (95% CI= 0.25 – 0.43). The prevalence of peptic ulcers was 30% and 60% in woman and man respectively. The highest environmental factor (cigarette) has been addressed in 30% (95% CI= 0.23-0.37) of patients. The prevalence of Helicobacter pylori was estimated in 62% (95% CI= 0.49-0.75) of patients.Conclusion:The results of this study show that prevalence of peptic ulcers in Iran (34%) is higher that worldwide rate (6% to 15%). There was an increasing trend in the prevalence of peptic ulcer over a decade from 2002 to 2016.

This study has highlighted the need to vaccination against rotavirus in Iranian population to reduce the prevalence of acute diarrhoea.Background: More than three million children in developing countries die from acute diarrhea annually. Rotaviruses and Adenoviruses are from the most important etiologic factors in acute gastroenteritis of children. Objectives: The aim of this study was to determine the prevalence of rotavirus and adenovirus among children with acute diarrhoea admitted to Abuzar Hospital in Ahvaz (Southwest Iran). Patients and Methods:In a descriptive, cross-sectional study over 1 year (September 2009 to August 2010, children who were admitted to Abuzar Hospital in Ahvaz with a diagnosis of acute diarrhoea were studied. Stools were examined with ELISA kits for detection of adenoviruses and rotaviruses. Results: Of 180 children in our study, 104 were boys (57.8%) and 76 were girls (42.2%), with a mean age of 12.86 months (1-60 months). Sixty-three (35%) had rotavirus infections (mean age, 11.57 months), and 6 (3.3%) had adenovirus infections (mean age, 8.17 months). We examined the seasonal distribution and found that 12 cases (19%) had occurred in spring, 11 (17.5%) in summer, 24 (38.1%) in autumn, and 16 (25.4%) in winter. There was no significant correlation between sex and viral agents causing acute diarrhoea (P = 0.96). Conclusions: This survey showed a high incidence of rotavirus infection (35%) in children with acute diarrhoea, especially in children under 2 years old. It seems that use of an appropriate vaccine could effectively prevent diarrhoea in this population.