Karachi is the major financial hub of Pakistan. The urban sprawl generates many sub financial hubs as well e.g. Saddar which is consider as CBD of metropolitan, specifically area along I.I. Chundrigar road is almost have offices and business set-up. The similar pattern has been emerged in many other places e.g. Shahrah-e-Faisal and Tariq road. Along all three major roads mixed-used development particularly commercialization has taken place prominently and these sectors emerged as main business Centre. The present study was aimed to assess the Land-Use/Land Cover (LU/LC), green cover and air quality index analysis through object based analysis on very high-resolution satellite imagery at Shahrah-e-Faisal. The obtained results showed that the combine three activities such as Shopping, Business and Trade (SBT), Social, Institutional and Infrastructure related activities (SII), and travel or movement (ToM) were occupied on 51.34% of land. The residential activities also make an attractive volume of proportion was up to 47.11%. Therefore, it can be the perfect example of smart growth if introduction greenways initiate more effectively along with some attraction spots for Leisure.