Recent development of new designer surfactants further spurs the development of micellar catalysis in water for chemical transformations and catalysis, providing reliable alternatives to the employment of organic solvents.

Tetrahedron Letters provides rapid dissemination of short accounts of advances of outstanding significance and timeliness in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Communications in Tetrahedron Letters are expected to represent brief summaries of preliminary work or initial results at the cutting edge of the field. Rapid publication of such research enables authors to transmit their new contributions quickly to a large, international audience. Tetrahedron Letters also publishes 'Digests', commissioned short reviews, highlights or perspectives, focusing on recent advancements in a field. Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services. Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center AUDIENCE. Organic chemist, bioorganic chemists.

The total syntheses of three C37 methyl‐alkenones with different degrees of unsaturation and of their 13C‐labelled analogues from commercially available starting materials are presented herein for the first time. These molecules are important to improve the reliability of the measurements and reconstructions of the sea surface temperature and salinity.

The Front Cover shows three C37 methyl‐alkenones with different degrees of unsaturation synthesized by marine organisms in relative amounts according to temperature and salinity conditions. Since these molecules are particularly resistant to degradation, they can be observed in marine sediments and their relative amounts are indicative of changes in oceans and climate during the Cenozoic Era. This manuscript describes the total synthesis of these substances, as required for chromatographic standards, as well as the synthesis of their 13C‐labelled analogues, which enable quality assurance and control procedures. The authors thank Thomas Bassano for creating the artwork. More information can be found in the Full Paper by F. Fabris et al.

C3-Symmetric tris-benzyl-O-substituted hexahydroxytriphenylene (HHTP) was prepared through selective ring opening with DIBAL-H in 48% yield (38% from HHTP in a two-step synthesis).