ΔADC at 2 weeks after the beginning of CRT is a reliable tool to early assess treatment response.

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ObjectiveTo assess the radiation dose and image quality of ultra‐low dose (ULD)‐CT colonography (CTC) obtained with the combined use of automatic tube current (mAs) modulation with a quality reference mAs of 25 and sinogram‐affirmed iterative reconstruction (SAFIRE), compared to low‐dose (LD) CTC acquired with a quality reference mAs of 55 and reconstructed with filtered back projection (FBP).MethodsEighty‐two patients underwent ULD‐CTC acquisition in prone position and LD‐CTC acquisition in supine position. Both ULD‐CTC and LD‐CTC protocols were compared in terms of radiation dose [weighted volume computed tomography dose index (CTDI vol) and effective dose], image noise, image quality, and polyp detection.ResultsThe mean effective dose of ULD‐CTC was significantly lower than that of LD‐CTC (0.98 and 2.69 mSv respectively, P < 0.0001) with an overall dose reduction of 63.2%. Image noise was comparable between ULD‐CTC and LD‐CTC (28.6 and 29.8 respectively, P = 0.09). There was no relevant difference when comparing image quality scores and polyp detection for both 2D and 3D images.Conclusion ULD‐CTC allows to significantly reduce the radiation dose without meaningful image quality degradation compared to LD‐CTC.

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