BACKGROUND AND OBJECTIVES: Spinal fusion through the anterior-to-psoas (ATP) technique harbors several approach-related risks. We used abdominal computed tomography imaging to analyze the L1-L5 ATP fusion approach measurements, feasibility, degree of obstruction by non-neurological structures, and the influence of patient characteristics on ATP approach dimensions. METHODS: The vascular window, psoas window, safe window, and incision line anterior and posterior margins for the ATP approach were measured on abdominal computed tomography imaging. The feasibility of approach and the presence of kidneys, ribs, liver, spleen, and iliac crests within the ATP approach were also measured. Correlation and regression models among radiographic measurements and patient age, height, weight, and body mass index (BMI) were analyzed as well as differences in approach measurements based on sex. RESULTS: Safe window and incision line measurements were more accommodating for the left-sided vs right-sided ATP approach. At L4-5, the ATP approach was not feasible 18% of the time on the left side vs 60% of the time on the right side. The spleen was present 22%, 10%, and 3% of the time from L1-4, while the liver was present 56%, 30%, and 9% of the time. The iliac crests were not observed within ATP parameters. Patient age, height, weight, and BMI did not strongly correlate with approach measurements, although ATP dimensions did differ based on sex. CONCLUSION: This study reports characteristics of the ATP approach including approach measurements, feasibility, non-neurological structures at risk, and influencing factors to approach measurements. While incision line measurements are larger for male patients compared with female patients at the lower lumbar levels, safe window sizes are similar across all levels L1-L5. The kidneys, ribs, spleen, and liver are potential at-risk structures during the ATP approach, although the iliac crests pose limited concern for ATP technique. Patient characteristics such as age, height, weight, and BMI do not markedly affect ATP approach considerations.
INTRODUCTION: A major shortcoming in improving care for cervical spondylotic myelopathy (CSM) patients is the lack of robust quantitative imaging tools to guide surgical decision-making.METHODS: A prospective cohort study enrolled fifty CSM patients who underwent cervical decompressive surgery. DBSI metrics assessed white matter tract integrity by fractional anisotropy, axial diffusivity, radial diffusivity, and fiber fraction. To evaluate extra-axonal diffusion, DBSI measures restricted and non-restricted fractions. Neurofunctional status was assessed by the mJOA, MDI, and DASH. Quality of life was measured by the SF-36 PCS and MCS. The NDI was used to measure self-reported neck pain. Patient satisfaction was assessed by the NASS satisfaction index. Support vector machine classification algorithms were used to predict surgical outcomes. Specifically, three models were built for each clinical outcome measure (e.g., mJOA), including clinical, DBSI, and combined models.RESULTS: Twenty-seven mild (mJOA 15-17), 12 moderate (12-14) and 11 severe (0-11) CSM patients were enrolled. Twenty-four (60%) underwent anterior surgery compared to 16 (40%) posterior surgery. The mean (SD) follow-up was 23.2 (5.6, range 6.1-32.8) months. The best performing model was for the prediction of the NASS satisfaction index, with an accuracy [95% CI] of 94.4 [94.3, 94.8]. Conversely, the worst performing model was for the NDI, with an accuracy of 73.8 [73.6, 74.5]. When predicting improvement in the mJOA, the clinically-driven model had an accuracy of 61.9 [61.6, 62.5], compared to 78.6 [78.4, 79.2] in the DBSI model, and 90.5 [90.2, 90.8] in the combined model.CONCLUSIONS: When combined with key clinical covariates, DBSI metrics predicted improvement after surgical decompression with high accuracy. These results suggest that DBSI may serve as a noninvasive imaging biomarker for CSM.
Introduction: Spinal epidural abscess (SEA) is a rare process with significant risk for morbidity and mortality. Treatment includes an extended course of antibiotics with or without surgery depending on the clinical presentation. Both non-operative and surgically treated patients require close follow-up to ensure the resolution of the infection without recurrence and/or progression of neurologic deficits. No previous study has looked specifically at follow-up in the SEA population, but the review of the literature does show evidence of varying degrees of difficulty with follow-up for this patient population.Methods: This retrospective review looked at follow-up for 147 patients with SEA at a single institution from 2012 to 2021. Statistical analyses were performed to assess differences between groups of surgical versus non-surgical patients and those with adequate versus inadequate follow-up.Results: Sixty-two of 147 (42.2%) patients had inadequate follow-up (less than 90 days) with their surgical team, and 112 of 147 (76.2%) patients had inadequate follow-up (less than 90 days) with infectious disease (ID). The primary statistically significant difference between patients with adequate versus inadequate follow-up was found to be surgical status with those treated surgically more likely to have adequate followup than those treated non-operatively.Conclusion: Improved follow-up in surgical patients should be considered as a factor when deciding on surgical versus non-operative treatment in the SEA patient population. Extra efforts coordinating follow-up care should be made for SEA patients.
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