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This research work presents a contribution to the areas of cosmetology and materials, focused on the use of natural products as exfoliating agents in solid soap. It consists of a literature review on the use of different exfoliating agents in cosmetics, a field survey to demonstrate the availability of these products in commercial stores, and tests to characterize their abrasive particles. The characterization in terms of shape and angularity of the abrasive particles of the selected exfoliating agents, was obtained through the Scanning Electron Microscopy-SEM tests, using the Scanning Electron Microscope - FEI Inspect 50™, of Particle Size and Shape Distribution. This research work consists of presenting the analysis of images of exfoliating agents, obtained through different methods, with the objective of classifying them according to their shape and angularity, which is one of the characteristics to be considered in an abrasive particle. The results obtained were in agreement with the literature in terms of shape and angularity, normally found in abrasive particles, as well as satisfactorily demonstrating the hypothesis of the use of kaolin, bentonite, rice microspheres, bamboo and apricot seed as exfoliating agents to be incorporated into solid soaps, motivating the expansion of research regarding the observation of their performance, but in this case with a tribological look on the subject.

Tuberculosis is a globally widespread infectious disease with elevated transmissibility and expressive mortality rate. It affects people throughout all age groups causing a strong economic impact on public health systems. Isoniazid, which was launched in the market in the 60's, has been the most effective antimicrobial drug for the treatment of tuberculosis so far. However, this is a long treatment with many adverse effects resulting in poor patient compliance. Therefore, it is necessary to develop oral intake systems that minimize the adverse effects of the drug to guarantee patients adherence to the treatment. Over the last decade, extensive research has shown that the development of controlled release systems is an effective way of addressing isoniazid's adverse effects. The intercalation of isoniazid in clay minerals such as bentonites present highly promising results. The present study review seeks to summarize and allow readers to understand the most recent published articles and research on this subject.

Tuberculosis is a globally widespread infectious disease with elevated transmissibility and expressive mortality rate. It affects people throughout all age groups causing a strong economic impact on public health systems. Isoniazid, which was launched in the market in the 60’s, has been the most effective antimicrobial drug for the treatment of tuberculosis so far. However, this is a long treatment with many adverse effects resulting in poor patient compliance. Therefore, it is necessary to develop oral intake systems that minimize the adverse effects of the drug to guarantee patients adherence to the treatment. Over the last decade, extensive research has shown that the development of controlled release systems is an effective way of addressing isoniazid’s adverse effects. The intercalation of isoniazid in clay minerals such as bentonites present highly promising results and accounts for one of the uttermost contributions of material engineering science to human medicine. The present study review seeks to summarize and allow readers to understand the most recent researches on this subject

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