Mexico holds the largest single bean production area in the world that is vulnerable to drought. Using field data and two future climate scenarios (RCP4.5 and RCP8.5) for the period 2020–2039, this study evaluated three common bean (Phaseolus vulgaris L.) cultivars planted under rainfed conditions at different densities in two locations in the north-central Mexican semi-arid temperate highlands. The sowing densities were 90,000, 145,000, and 260,000 plants ha−1 established in single rows (SR), three rows (3R), and six rows (6R), respectively. The climate change scenarios were derived from an assembly model integrating 11 general circulation models (GCM) selected for Mexico with a 30” arc resolution. The baseline climate was for the period 1961–2010. The ALMANACMEX model (USDA-ARS-INIFAP, Temple, USA) was parameterized and evaluated and then re-run using the climate scenarios. Beans planted at 6R showed the highest increase in seed yield in both climate scenarios, although the response varied by cultivar and time periods. For the growth habit III cultivars, Flor de Mayo Bajio showed no difference in yield, while Pinto Saltillo, a drought-resistant cultivar, showed increases of 13% to 16% at 6R only until 2033. Growth habit I cultivar Azufrado 2 showed more than 60% increases at 6R in both climate scenarios for the full period 2020–2039. These results suggest that considering the projected climate conditions, high sowing densities may be a viable agronomic option for common bean production under rainfed conditions in semi-arid temperate regions, such as the highlands of Mexico, in the near future; however, the selection of the cultivar is a key element to consider in this regard.