BACKGROUND AND OBJECTIVES: Neutrophils constitute an essential part of our immune system against invasive microorganisms. Neutropenia is a frequent problem encountered in hospitalized children with myriad implications on duration of hospital stay as well as outcome. This study was conducted to study clinical prole and short term outcome of hospitalized neutropenic children. METHODS: This observational study was done at our tertiary care level teaching hospital over two years period from April 2018-March 2020. We included 56 hospitalized children aged <15 years with absolute neutrophil count (ANC) <1500/ cu mm. Necessary investigation were done to identify the cause of neutropenia. Clinical features, admission diagnosis, duration of neutropenia, duration of hospital stay, complications and outcome were studied. Such children were followed up for 4 weeks. RESULTS: Mean age was 8.8 years (S.D 2.7 years). Mild neutropenia was seen in 48.2%, moderate neutropenia in 33.9% and severe neutropenia was seen in 17.9% cases. Mean ANC was 1021/cu mm (SD 324) whereas the mean duration of neutropenia was 4.7 days (SD 2.4 days). Infections were the commonest etiology of neutropenia (dengue, malaria & enteric fever were the commonest infections). Thrombocytopenia was seen in 31(55.4%) of such children. Mean duration of thrombocytopenia was 6.24 (SD 2.17) days. Mean & median duration of hospital stay was 8.24(S.D 4.3) days and 7 days respectively. 47 (83.4%) children were discharged and 9 (16.6%) children died. Neutropenia normalized in 48 (85.7%) children by end of rst week. No children had persistent neutropenia during the 4 week follow-up period. CONCLUSION: Infections are the commonest cause of transient neutropenia in hospitalized children with dengue, typhoid and malaria being the common etiologies. The length of hospital stay as well as the duration of neutropenia increased with the severity of neutropenia and there was an inverse relation of these to the age. Our study also shows that most of the episodes of acute transient neutropenia recover without major complications
Hypertension during pregnancy is a highly variable disorder unique to pregnancy and a leading cause of maternal and fetal/neonatal morbidity and mortality. Pregnancy-induced hypertension is the general classification for hypertension diseases during pregnancy, which include pregnancy-induced hypertension usually after 20th week of gestation (without proteinuria), pre-eclampsia (with proteinuria), and eclampsia (pre-eclampsia with convulsions). This disease is responsible for high maternal and perinatal morbidity and mortality rates, and is one of the main public health problems. Hence based on above findings the present study was planned for Assessment of Neonatal Outcomes in Eclamptic Mothers Admitted to NMCH, Patna, Bihar. The present study was planned in Department of Pediatrics, Nalanda Medical College and Hospital, Patna, Bihar, India. The study was planned from March 2019 to October 2019. In the present study 50 females admitted with eclampsia or with pre-eclampsia but subsequently developing eclampsia were enrolled. Also the control females were also evaluated for comparative evaluation. The data generated from the present study concludes that Prevention of prematurity, treatment of morbidities & prevention of infection among infants should be done to reduce the PMR and improve perinatal outcome. Thus High risk pregnancy should be identified prospectively and then given special care, perhaps a major impact on overall perinatal loss could be reduced. Keywords: Eclamptic Mothers, Patna, Bihar, etc.
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