OBJECTIVE: Intrauterine Pressure Catheters (IUPC) are thought to create a pathway for contamination and ascending infections. We sought to estimate the risk of chorioamnionitis associated with IUPC use in term labor. STUDY DESIGN: This is a retrospective cohort study of term (37 weeks), singleton pregnancies who labored at our tertiary care center from 2005 to 2018. The primary outcome of chorioamnionitis was defined as maternal intrapartum fever (single oral temperature of >39 C or 38e38.9 C for 30 minutes) and one or more of the following: maternal leukocytosis, purulent cervical drainage, or fetal tachycardia. The primary exposure was the presence of an IUPC documented in the medical record. Cox proportional hazard regression was used to model the effect of cervical examinations on the risk of chorioamnionitis while adjusting for adjusted for number of cervical exams, epidural use, meconium, smoking, GBS, parity, BMI, duration of rupture, labor induction and cesarean section. RESULTS: 20,579 women met inclusion criteria and1,039 (5%) women were diagnosed with chorioamnionitis. Of the subjects diagnosed with chorioamnionitis, 185 (17.8%) had IUPCs compared to 22.5% in women not diagnosed with infection (p<0.001). IUPCs were not associated with increased rate of chorioamnionitis after adjusting for potential confounders (hazard ratio [HR] 0.6, 95% confidence interval [CI] 0.5-0.7; p¼<0.001). Presence of IUPCs was higher in women undergoing unplanned cesarean delivery (30.6% versus 21.1% in women undergoing vaginal delivery, p¼<0.001). Meconium rates were not higher in women with IUPCs (IUPC 20.0% versus no IUPC18.8 p¼0.06) CONCLUSION: In contrast to prior work, routine use of internal monitoring in laboring patient did not increase the risk of chorioamnionitis. Internal monitors should not be avoided during term labor management.

The UC San Diego MADURA Mentorship Program, funded by an R25 National Institute on Aging grant, has goals to improve diversity in Aging and Alzheimer’s Disease (ADRD) research and clinical practice. MADURA strives to improve retention and academic success of its URM trainees, and to increase graduate/medical school applications and/or entry into Aging/ADRD careers. Mentees receive paid research experience, skills training, peer support, seminars, and additional professional development opportunities. Given local demographics and Co-Investigator expertise, MADURA recruits primarily Hispanic/Latinx (H/L) students, and other URM students. Non-exclusive racial identifications of 32 Year 1 mentees were: 69% H/L, 9% Black/African American, 22% Asian and 31% other race. 72% met NIH criteria for Disadvantaged Backgrounds. As of June 2021, 100% of students completed surveys assessing Racial Microaggressions and Imposter Syndrome experiences, and Professional Self-efficacy. This poster will define the concepts, discuss relevance for URM student success and retention, and present student data on each topic. As examples, 56% of trainees experienced overt discrimination and 72% reported having experienced microaggressions at least occasionally, as undergraduates. As related to Imposter Syndrome, 62% secretly worried that others would find out that they are not as bright and capable as others think. Half attributed accomplishments to being a “fluke,” or due to reasons other than true merit. Still, in terms of Professional Self-efficacy, 62% of mentees thought it moderately or very likely that they would succeed as an Aging/ADRD researcher. The authors will make specific suggestions for optimized URM training and mentorship program content, and provide resources.

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