A highly sensitive amperometric Prussian bluebased hydrogen peroxide sensor was developed using 3D pyrolytic carbon microelectrodes. A 3D printed multielectrode electrochemical cell enabled simultaneous highly reproducible Prussian blue modification on multiple carbon electrodes. The effect of oxygen plasma pretreatment and deposition time on Prussian blue electro-deposition was studied. The amperometric response of 2D and 3D sensors to the addition of hydrogen peroxide in μM and sub-μM concentrations in phosphate buffer was investigated. A high sensitivity comparable to flow injection systems and a detection limit of 0.16 μM was demonstrated with 3D pyrolytic carbon microelectrodes at stirred batch condition
and dyslipidemia which potentially effect on mortality were similar. The death rate adjusted for all of the variables was significantly lower in RARP than RT patients (HR[.767, 95% CI .072-.818, p<.0001). From the age of 75 yrs, more patients underwent RT (N[3,239) rather than RARP (N[2,478). The adjusted death rate for this particular patients was similar (HR[.98, 95% CI .897-1.07, p[.649). When adjuvant therapy was excluded from each modality (ADT from RT group and RT from RARP group), the adjusted mortality rate was significantly lower in RARP group regardless of age cut-off.CONCLUSIONS: With limitation of population based study provided by medical insurance information, RARP performed in elderly patients seems to be an efficient therapeutic option replacing RT which had long been recommend for this particular age group of patients, providing similar survival for patients older than 75 yrs and superior survival for relatively younger counterparts (70-74 yrs).
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