BackgroundLeprosy is a chronic infectious disease endemic in some undeveloped areas, and still represents a public health problem in Brazil. Therefore, the control of this endemic disease depends necessarily on the institution of correct treatment and containment of treatment dropout. This study aims to conduct a systematic review of published studies on treatment dropout of leprosy.MethodsWe conducted a systematic review of articles on treatment dropout of leprosy, published between january 2005 and april 2013, on MEDLINE and SciELO databases. The search was performed using the MeSH terms: “leprosy”; “patients dropouts” and the keywords: “leprosy, treatment” and “noncompliance, leprosy” in association, beside the equivalents in Portuguese.ResultsThere were originally 196 references. After analyzing the titles and abstracts of articles, 20 articles were obtained and included in the final sample.DiscussionLeprosy is a notifiable disease known as its disfiguring capability and the high rate of non-compliance to treatment. The low adhesion is responsible for the remaining potential sources of infection, irreversible complications, incomplete cure and, additionally, may lead to resistance to multiple drugs. Many factors are responsible for the interruption or dropout treatment: socioeconomic factors, education level, knowledge about the disease, lack of efficiency of health services, demographics, side effects of drugs, alcoholism, among others.ConclusionThe recent scientific literature about the subject diverge regarding the factors that most affect the dropout problem in treating leprosy patients. However, better integration between professionals and users, and greater commitment of the patient, are common points among the authors of the studies.
About 24.7% of women in the sample never had a mammography. According to the findings, the lack of breast cancer screening is associated with social and racial inequalities.
Stroke is an example of neurological diseases that can commonly drives Excessive
Daytime Sleepiness (EDS). Extensive strokes with brain edema can leave a brain
herniation and coma. Other causes of EDS after stroke are strategic lesions at
Thalamus and brainstein. A 56-year-old man, right handed, with hypertension and
hypercholesterolemia was admitted at Emergency Room due to 5 days onset of EDS,
memory impairment, and left-sided weakness. A brain magnetic resonance imaging
showed paramedian thalamic hyperintensity with rostral midbrain hyperintensity
extending along the pial surface of the interpeduncular fossa. The artery of
Percheron (AP) is an unusual anatomical variation that originates from the
posterior cerebral artery and irrigates the paramedian regions of the thalamus
and part of the midbrain. It is important the clinical suspicions with detailed
drowsy patients history. Awareness of the clinical and neuroimaging features of
this stroke syndrome is essential for timely diagnosis and appropriate
management.
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