A 51-year-old white Brazilian female woman initially presented symptoms similar to migraine and chronic pain after the birth of her second child. After confusing diagnosis and continuous use of painkillers, the patient presented drug-induced hepatitis. A complete neurological evaluation was performed, where the imaging tests proved the existence of multiple sclerosis (MS). According to our knowledge, this is the first reported case in the literature. Thus, our study highlights the importance of alerting physicians in closely observing the variables presented in each neurological case.